Search results for " chromatography" in Posters

Poster To Speed Up the Process Optimization of the Described Biosimilar Product
This example describes a standardized workflow using a highthroughput process development (HTPD) approach: chromatography resin and running conditions were selected based on experience and adapted to …

Poster Rapid Process Development of a CIEX Step for a Biosimilar
A standardized workflow was adapted using a high throughput process development (HTPD) approach: chromatography resin and running conditions were selected based on experience and adapted to meet requi…

Poster Impact of sporicidal agent on MabSelect SuRe™ protein A resin lifetime
However, many of the protein-based chromatography resins used in purification of biomolecules are sensitive to harsh sanitization conditions. In this application note, the effects of treating MabSelec…

Poster Integration of continuous upstream and downstream operations in mAb production
We describe the integration of a high-performing upstream cell culture process with downstream purification utilizing emerging technologies such as periodic counter-current (PCC) chromatography and st…

Poster Modes of controlling charge variant distribution in Mab production
Furthermore, the MAb charge variant clearance in the downstream chromatography polishing step was evaluated.

Poster Optimizing dynamic binding capacity and aggregate clearance in an mAb polishing step
Capto™ S ImpAct is a strong cation exchange (CIEX) chromatography medium (resin) designed for monoclonal antibody (MAb) polishing steps. In this study, optimization of binding conditions targeting h…

Poster Accurate comparability assessment of a biosimilar interferon in process development
This application note describes how to achieve accurate comparability assessments using Biacore™ T200 and Amersham™ WB system in the development of a biosimilar. This is exemplified in this study…

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