Search results for " disposable"
Article
The use of Xcellerex™ mixing system as slurry tank when packing chromatography columns
The system is complete with motor and controls, and an irradiated USP Class VI, single-use, low-density polyethylene plastic bag equipped with a disposable bottom-mounted impeller. The connection betw…
Article
Flexibility in Biopharmaceutical Manufacturing
Existing large-scale stainless steel plants, medium-volume launch facilities, and low-volume disposable units, complimented by specialized emerging market service units are all in evidence.
Oth…
Article
Supply Chain Challenges for Single-Use Systems
In a fully disposable or hybrid facility, however, because pieces of equipment (e.g., reactors, transfer tubing, holding vessels) are now consumables, the supply to the manufacturing facility is more …
Article
Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
This year’s study covers such issues as: new product needs, facility budget changes, current capacity, future capacity constraints, expansions, use of disposables, trends and budgets in disposables, t…
Article
Automation Trend in Fill/Finish Reduces Contamination Risk
ABL reported that the new system uses a disposable product-contact path to limit cross contamination and is contained in a RABS to increase sterility assurance level (SAL) and reduce the risk of rando…
Article
Unifying Continuous Biomanufacturing Operations
… reduction in human error has to be carefully balanced with potential new errors related to handling disposable perfusion equipment and the proper control of perfusion.
Karst et al. highlighted a…
Poster
Case Study: Improve Process Economy by Cycling of Prepacked Chromatography Columns
The challenge, however, of using disposable technologies relates to the often higher consumables and operating cost as compared with stainless steel solutions. As projects are scaling up to manufact…
Article
Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
Compared with facilities using stainless steel columns, the use of disposable ReadyToProcess Adsorber membranes minimizes the number of non-value-adding steps in process development, such as cleaning …
Article
Process Chromatography Selection for Downstream Processing Applications
Industry experts discuss best practices for selecting a separation technology.
By Caroline Hroncich
Process chromatography has changed significantly since it was first introduced to the biop…
Article
An Integrated Approach to Ensure the Viral Safety of Biotherapeutics
Testing product and process intermediates alone is helpful, but does not provide a complete solution to viral safety. This article proposes integrated solutions for systemic and proactive viral risk m…