Search results for " bioprocessing"
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Sterilization Trends for Single-Use Consumables
Single-use (SU) technologies increasingly find use today at all phases of the drug development cycle from preclinical to commercial manufacturing. As the biopharmaceutical market continues to …
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Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
Chahal, Pharmaceutical Bioprocessing, (2014).
5. R. Kunert and D. Reinhart , Appl Microbiol Biotechnol, 100 3451–3461 (2016).
6. R. Gilbert, Cell & gene therapy insights, 6 (1) 143-148 (2020).…
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Cytiva Introduces the Xcellerex Automated Perfusion System
The APS system comes equipped with filter switching, liquid management, and cell bleed to reduce risk of human error and increase process robustness.
Cytiva announced on Sept. 16, 2020 that it i…
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Achieving Process Balance with Perfusion Bioreactors
Advances in single-use technologies, sensors, and cell retention systems facilitate processes designed for the long run.
By Cynthia A. Challener
MG/Stock.Adobe.com
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Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
The result was a new web utility named GlycanAnalyzer, developed in a collaboration between New England Biolabs and the Bioprocessing Technology Institute (A*STAR, Singapore). The program automates an…
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Establishment of New Modern Plasma Fractionation Facilities in Asia
You are part of the organization committee for the 3rd BioProcessing Asia Conference, which will take place November 12-15, 2018 on Langkawi, Malaysia, and with a session dedicated to plasma fractiona…
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Biopharma Says It Has an Evolution in New Technologies and Processes
Panelists suggested that a complete end-to-end continuous manufacturing process for bioprocessing may be an elusive goal; however, continuous operations may help in some segments of a full process.
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Reducing Cross-Contamination Risks in Process Chromatography
“With typical bioprocessing tools, a lot of effort and care goes into cleaning and cleaning validation of contact surfaces since any contamination in the purification process can be detrimental to the…
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Unifying Continuous Biomanufacturing Operations
Integrated continuous bioprocessing is already regularly being achieved in small research labs, according to Bonham-Carter, but has not yet made its mark in commercial, cGMP environments (8).
Pr…
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Single-use technologies in downstream process intensification
In bioprocessing, thorough cleaning is critical in order to take full benefit of the resin by removing impurities. When using conventional chromatography solutions, cleaning and cleaning validation …