Search results for " single-use" in Articles / App Notes
Article
Improving Upstream Predictability
Leveraging PAT and sensor technology, it will feature a modular design and use portable 2000-L bioreactors and vessels and single-use bioreactors.
At the contract development and manufacturi…
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Flexible Facilities for Viral Vector Manufacturing
The facilities use single-use systems. Murphy says the primary benefit for single-use systems is eliminating the need to perform cleaning validation on reused product contact equipment.
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Making the Move to Continuous Chromatography
Some systems come with flow paths that are designed to be cleaned and reused, while others are flow paths that are single-use. Some systems come with dynamic control functionality—process analytical t…
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Lessons Learned Accelerate Vaccine Development
High-throughput and single-use technologies are also being leveraged to accelerate key aspects of manufacturing processes, such as determination of appropriate media, resins for purification, formulat…
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CMOs Continue to Improve Overall Biomanufacturing Performance
CMOs’ love affair with single-use devices has been well documented. Indeed, single-use implementation and integration is a much larger focus for CMOs than it is for biotherapeutic developers. And as t…
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Tools and Processes for Mature and Emerging Therapies
…ns for upstream and downstream systems, and introduced equipment, supplies, columns, media, buffers, single-use systems, and ancillary equipment to promote process capabilities and reliability.
N…
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The Outlook for CMO Outsourcing in 2019
The industry is starting to see a major trend for CMOs adding 1000–2000-L single-use bioreactor process lines for commercial manufacturing as products currently in development manufactured with single…
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Scaling Up Novel Therapies
Cell culture improvements were followed closely by small-scale single-use technologies. As a result, on the bacterial side, developers can now go into production using 100- to 300-L single-use reactor…
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Optimizing Late-Stage and Commercial Cell-Culture Processes
In addition, development of intensified processes and integrated continuous processing (with single-use technology and sensors/control) have also contributed to increasing titers, maintaining consiste…
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Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
Also unpredicted 15 years ago was the rate of adoption of single-use devices. While 15 years may seem a long adoption cycle, in the bioprocessing industry, where regulators are involved in most decisi…