Search results for " single-use" in Articles / App Notes
Article
Challenges and Trends in Biopharma Facility Design
BioPharm International spoke with Daniella Kranjac, head, evaluation and offering, Enterprise Solutions, at Cytiva; Mario Philips, president of Single-Use Technologies at Pall Life Sciences; Par Almhe…
Article
Advanced Technologies Facilitate Scale-up and Technology Transfer
Single-use solutions
One of the most efficacious ways to revamp older processes as required by FDA is to upgrade with single-use technologies, according to Helene Pora, vice-president of single-us…
Article
Overview of a scale-up of a cell-based influenza virus production process using ReadyToProcess equipment
…am and downstream processes for the production of a cell based live attenuated influenza virus using single-use ReadyToProcess technology (Fig 1).
Introduction
Egg-based production is the…
Article
Reconciling Sensor Communication Gaps
Single-use systems generally suffer from a “sensor gap” related to the need to balance measurement accuracy against the well-known benefits of single-use processing, including the avoidance of cleanin…
Article
Advances in Sterilization Technologies for Overcoming Viral-Vector Manufacturing Challenges
…grity test (PUPSIT) and a post-use integrity test in situ, the potential for leak development within single-use manifolds during installation or processing, and the need to minimize hold-up volumes, …
Article
Setting Up Bioprocessing Systems for Digital Transformation
Single-use systems risks
The same principles and need for data integrity apply to single-use systems but at a higher volume, says Lenich. He emphasizes that, in addition to maintaining data integr…
Article
Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
The increasing popularity of single-use bioreactor systems and continuous processing techniques have brought both new opportunities and challenges to upstream bioprocessing. Together, these trends hav…
Article
Strategizing for Rapid Changeovers in Biologics Manufacturing
“Pre-gamma irradiated single-use flow paths for all unit operations, standardized pre-sterilized tubing assemblies to connect unit operations, and aseptic quick connectors (rather than welding or heat…
Article
What’s New in Upstream Technologies
Single-use sensor and adapter
Emerson’s Rosemount 550pH sensor and Rosemount 550DW dissolved oxygen (DO) sensor adapter provide improved sensor stability for single-use bioreactors and are suited …
Article
Improving PAT for Biologics
…e variability of raw materials (particularly living organisms), and the move from stainless-steel to single-use equipment. The recent emphasis on establishing a thorough understanding of the manufact…