Search results for " single-use"
Article
Assessing leachables risk over a complete single-use, mAb process
In an article, process equipment-related leachables are mapped over a complete single-use mAb process at pilot scale.
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Article
Evaluation of Fibro PrismA for Scalable Single-Use mAb Purification
Bayer worked with Cytiva to evaluate a fiber-based alternative, Fibro PrismA, to determine its potential as a truly single-use mAb capture technology. The team assessed scalability from lab- to proces…
Article
Developing a Closed, Connected Single-Use mAb Purification Process
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Learn more on this case study to set up a closed and connected single-use monoclonal antibody (mAb) purification process that addresses a perfusion upstream process. In the Pr…
Article
Purposeful Design and Development of a Next Gen Single-use Bioprocess Film
Introducing Fortem™ film, a platform film technology built specifically for the single-use product portfolio. Fortem film is purposefully designed and developed with a carefully selected raw material,…
Article
Single-Use Workflow for Recovery of a Domain Antibody from E. coli Culture Feed in an Automated Manner
This application note demonstrates the performance of the automated ÄKTA™ readyflux single-use filtration system in microfiltration applications. Here, a domain antibody (dAb) expressed in E. col…
Article
Single-Use Extractables and Leachables: Cytiva's Alignment with the BPOG Protocol
For end users who are adopting single-use (SU) equipment as a manufacturing strategy, this situation becomes unwieldy. The need for a standard approach both to the generation and to the reporting stru…
Poster
Validation of Cytodex™ Gamma microcarrier-based virus production in single-use bioreactor systems
… medium using spinners, WAVE Bioreactor™ 20/50, ReadyToProcess WAVE™ 25, and Xcellerex™ XDR-10 single-use bioreactor systems. Cells in each WAVE Bioreactor system were infected with influenza virus a…
Article
Single-use technologies in downstream process intensification
This problem can be addressed by using single-use technologies, which eliminate the need for cleaning and cleaning validation.
To learn more about downstream single-use opportunities and other way…
Article
E. coli growth and Dab expression in single-use and stainless steel fermentors
This application note describes the performance of the Xcellerex™ single-use XDR-50 MO stirred-tank fermentor in an E. coli domain antibody (Dab) production process developed for a stainless steel …
Article
Single-Use and Continuous Processing Technologies Change Facility Design
Viewing Changes in Pharmaceutical Facility Design
Single-use systems, continuous processing and isolator technology use a smaller footprint. Experts predict how the facilities of the future may …