Search results for "Mabs" in Articles / App Notes
Article
Antibody Production Workflow
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Antibody-based therapies have evolved beyond monoclonal antibodies (mAbs) to include bispecific antibodies, antibody fragments, antibody-drug conjugates (ADCs), and m…
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Start-to-Finish Connected Manufacturing
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We understand that evaluating new biomanufacturing technologies that promise efficiency gains is challenging. That’s why we are demonstrating our mAb process that te…
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Platform for Purification of VHH-type Antibody Fragments
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Protein A affinity chromatography resins have been used to purify monoclonal antibodies (mAbs) by the bioprocess industry at all scales for a long time. Howev…
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Technology Innovations Improve Process Chromatography Performance
As technology matures, inefficiencies and process limitations in downstream process chromatography are improved.
By Feliza Mirasol
Selecting an appropriate separation technology fo…
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Step Up to GMP Manufacturing or Outsource to a CDMO: Considerations and Tips
Whether you are developing a new monoclonal antibody (mAb), cell therapy, gene therapy, or large-molecule biologic drug, the decision to tackle GMP manufacturing in-house or work with a contract devel…
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Improving Upstream Predictability
Better understanding and control of cell behavior is yielding benefits, upstream and beyond.
By Agnes Shanley
In the earliest days of biotech, developers often struggled to sust…
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A New Paradigm in Process Development
Accelerate biologic manufacturing of mAbs, vaccines, and novel biotherapies. Download this e-book for case studies and insights from Janssen, Roivant Sciences, and mAbxience.
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Scaling Up Novel Therapies
Used almost exclusively for monoclonal antibodies (mAbs), platforms help shorten development times, particularly early in development, Ransohoff says. They also allow manufacturers to leverage perform…
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Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
al, MAbs 9, 1349–1359 (2017).
15. S. Vainauskas, et. al, Sci. Rep. 8 (1), 9504 (2018).
16. T. Walsh, et. al, Bioinformatics online, DOI: 10.1093/bioinformatics/bty681, Aug. 7, 2018.
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Article
Process Economy Simulations on a Protein A Capture Step
This application note gives calculation examples that highlight scenarios where the enhanced capacity and alkaline‐stability of MabSelect PrismA can provide process economic benefits to large‐scal…