Search results for " bioreactor"
Article
Simplifying Cell Culture Expansion
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Controlled perfusion in a closed, single-use bioreactor can cut the complexity from your cell culture expansion process, making it possible to go from seed trai…
Article
Technology Innovations Improve Process Chromatography Performance
…use technologies, better characterization of raw materials, and the use of more precisely controlled bioreactors, improvements in downstream processing have not kept pace, says Nandu Deorkar, vice-pr…
Article
Fortem: One Film for Single-Use Bioprocessing
Single-use bags can now be found at every stage of bioprocessing: bioreactor and mixing systems, harvest and collection, purification, and liquid and powder storage and transportation. Thus, Cytiva ha…
Article
Automating the Biomanufacturing Process
One supplier has extended and improved its sensor portfolio, by, for example, including a sensor that measures biomass in the United States Pharmacopeia bags used for rocking motion-based bioreactors …
Article
Reducing Cross-Contamination Risks in Process Chromatography
Today, single-use bioreactors are widely used for biologic drug manufacturing, and downstream disposable technologies for commercial-scale production operations are being introduced and increasingly a…
Poster
Scale-up of CHO fed-batch cultures in HyClone™ ActiPro™ medium supplemented with Cell Boost™ 7a and 7b
In addition, scalability of the culture process was demonstrated in 2 and 50 L bioreactor cultures. Cell density and protein production were shown to be comparable between scales. Protein yields reach…
Article
Continuous Processing for the Production of Biopharmaceuticals
The whole assembly had the capacity to produce end-to-end continuous production from bioreactor to the polished product (Figure 2). The key distinguishing features of this facility were uninterrupted …
Article
Adherent Cell Culture in Biopharmaceutical Applications: The Cell-Detachment Challenge
…he ongoing efforts of the authors to incorporate plasmonic cell-detachment features into the Bolt-on bioreactor (20). Refinement of the methods that have great potential for enabling efficient cell d…
Article
Biopharma in 2015: A Year for Approvals and Innovations
…g of a monoclonal antibody
Highly efficient inoculum propagation in perfusion culture using WAVE Bioreactor™ systems
The Use of Dynamic Control in Periodic Counter-Current Chromatography
Pu…
Article
Taking a “Development-by-Design” Approach to Cell Therapies
Equipment Evolves
In the bioreactor area, there is great interest in moving from 2-D to 3-D processing to enable the processing of the cell volumes required, something that companies such as Israe…