Search results for " filtration" in Articles / App Notes
Article
Evaluating E&L Studies for Single-Use Systems
For example, a bag or a filter used for the final filtration of bulk drug substance will have a significantly higher rating compared with the components used in the upstream process steps.
Figure …
Article
Protein Characterization Using SEC: Three Webinar Takeaways
The possibility to separate molecules by size under native conditions is powerful in protein analysis. With more than thirty years in protein science, Åke Danielsson, Research Director at Cyti…
Article
Advancing Single-Use Technology Through Collaboration
Even though all manufacturers deal with the same basic steps, such as filtration and chromatography, there are almost no commonalities within the designs of single-use systems, because each organizati…
Article
Improving Process-Scale Chromatography
Advances in technology are increasing the productivity and efficiency of commercial-scale chromatography bioprocesses.
By Cynthia Challener, PhD
Chromatography is a crucial step in the purif…
Article
Safety Drives Innovation in Animal-Component-Free Cell-Culture Media Technology
Advances in cell culture media technology have helped achieve safer biologics.
By Tom Fletcher, Holden Harris
Regulatory expectations for cell-culture-based biologics production processes ch…
Article
Perfusion in the 21st Century
Furthermore, protein retention has been reported when working at high densities with filtration systems. Manufacturers have access to more sophisticated media and more stable cell lines with new selec…
Article
An Integrated Approach to Ensure the Viral Safety of Biotherapeutics
… operations; air pressure differential; HVAC; treatment of production water; control and appropriate filtration of production gases; waste treatment and waste disposal; and a pest control program
…
Article
Tools for Continuous Bioprocessing Development
For example, perfusion process development experiments (21) using a 4-L working-volume Wave bag and alternating tangential flow (ATF) or tangential flow filtration (TFF) cell-retention filter, consume…
Article
CMOs Continue to Improve Overall Biomanufacturing Performance
Many are also using or evaluating a number of technologies, including:
• Membrane-based filtration technologies
• Ion-exchange membrane technologies
• Ion-exchange technologi…
Article
Re-use of Protein A Resin: Fouling and Economics
Sofer, “Lifespan studies for chromatography and filtration media” in Process Validation, A. S. Rathore and G. Sofer, Eds. (Marcel Dekker, 2005), pp. 169-203.
20. A. S. Rathore, “Qualification of a…