Search results for "development"
Article
Developing a HIC polishing step for removal of mAb aggregates
This article describes the development of a flow-through (FT) polishing step using hydrophobic interaction chromatography (HIC) to remove mAb aggregates.
It includes:
- The use of HTPD plate…
Article
Free eBook: Considerations for smarter and faster process development
What you will learn:
Industry drivers to go smarter and faster in process development
Strategies for more efficient upstream process development
Strategies for more efficient down…
Article
Process Development and Control for New Modalities
Lack of pre-determined process and analytical platforms for these modalities often translates to longer development times. New modalities are more difficult to fully characterize due to their complexi…
Article
High-Throughput Process Development Handbook
Efficient development of the manufacturing process is a crucial component of the overall project plan. However, screening optimal process conditions can be time-consuming and tedious. In addition, ste…
Article
Biosimilars Development and Supply: How Complex Can the Process Be?
High-quality, reliably supplied biosimilars offer additional therapeutic choices to patients and other key stakeholders; however, development and supply of these complex medicines are scientifically c…
Article
Accelerating CMC - The future of process development is in silico
Simulation for in silico process development is becoming a viable option to reduce the time needed for chemicals, manufacturing, and control (CMC) activities and increase process understanding. Advanc…
Tip
Considerations for smarter and faster process development
What you will learn:
Industry drivers to go smarter and faster in process development
Strategies for more efficient upstream process development
Strategies for more efficient downstream proce…
Article
Chromatography Process Development Going Smarter
Especially, he explains how methods such as raw material insights and mechanistic modeling enable accelerated process development and improve general process understanding, robustness, and performance…
Article
High-Throughput Process Development in Biopharma
During early process development, high-throughput process development (HTPD):
• Shortens development time
• Increases the amount of information available
• Enables reduction of sample a…
Article
Free On-Demand Webinar: Smart Process Development of Chromatography Steps
Join Peter Hagwall as he reviews three smart process development tools that enable reduced timelines and improved process outcomes:
1.
In-silico process development and data-driven decisions…