Search results for " high-throughput" in Articles / App Notes
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Combining Microbioreactors and Advanced Statistical Techniques to Optimize a Platform Process for a New Host-Cell Line
First, the availability of high-throughput miniature bioreactors has made it possible to evaluate many more conditions. This has enabled design of experiment (DoE) approaches, such as response surface…
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Fermentation for the Future
Given that there is a strong dependence between protein structure and performance of protein-based drugs, extensive refolding know-how and high-throughput screening capabilities are key to achieving t…
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Predicting Progress in Protein Aggregation
As a result, significant efforts have been invested in understanding the mechanisms behind aggregation and the establishment of predictive models and more advanced analytical techniques, particularly …
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Digitalization: The Route to Biopharma 4.0
Fully Automatized High-Throughput Enzyme Library Screening Using a Robotic Platform. Biotechnol Bioeng. 2016, 113 (7), 1421–1432. DOI: 10.1002/bit.25925.
4. Bielser, J. M.; Domaradzki, J.; Souqu…
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Program finalized for the 6th HTPD and smart PD conference
As previously announced, the 6th International Conference devoted to High-Throughput Process Development (HTPD) and smart PD, will be held October 30-November 2, 2023 in Valetta, Malta. The HTPD confe…
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HTPD 2023 conference is coming up. What will be discussed and what happened last time?
…tories here:
A new dawn for high throughput process development
Applications of modern high-throughput process development
Smart process development and a look into the future
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Cell-free Expression Systems Pose Cell Culture Alternative
“For preclinical, we’ve already seen quite a lot of antibody production and high-throughput expression screening done in lab scale. But for clinical, the scale-up production is still under development…
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Virus-like Particles as Therapeutic Moieties of the Future
SPR offers a high-throughput, rapid, label-free method to detect association of VLPs with their targets in real time (26).
An IVRP assay reports the qualitative and quantitative epitope compos…
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A Look at the Affinity Chromatography Landscape
He does note that the use of standard and multimodal resins and high-throughput screening technologies greatly aid in defining separation techniques.
Most importantly, Heldin adds that affinity…
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Scaling Up Novel Therapies
Some high-throughput tools are already used early on and in process characterization, allowing users to run many experiments in parallel at smaller scale, with less material and in less time. One exam…