Search results for " productivity" in Articles / App Notes
Article
Mapping a Route for Cell and Gene Therapy Process Development
“Gene therapies require high productivity to meet the high dose demands. The productivity largely depends on the harvest titer and downstream process yield. Moreover, the product design at the molecul…
Article
Maximum Output Starts with Optimized Upstream Processing
Equipment suppliers, contract manufacturers, and biopharmaceutical companies are implementing new bioprocessing solutions and manufacturing strategies to increase efficiency and productivity, forging …
Article
Assessing Manufacturing Process Robustness
A structured assessment process can determine compliance to lifecycle process-validation requirements for biopharmaceuticals.
By: Ajay Pazhayattil, Sanjay Sharma, Amol Galande, Marzen…
Article
Platform Approach Speeds Process Development
…rs, host cell portfolio, cell line generation, cultivation media, and process design to increase the productivity and overall product yields in a biopharmaceutical process for the production of recom…
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Impact of Media Components on CQAs of Monoclonal Antibodies
A deeper insight in understanding of metabolism and cell mechanisms is required to define strategies for providing effective means to reduce by-products and increase productivity d quality of biologic…
Article
A Look Ahead at BioPharma Manufacturing and Regulation
The FDA talks about the changing scope of regulatory science.
Regulatory science underpins innovation and practices in drug manufacturing. The most common definition of r…
Article
Understanding Validation and Technical Transfer, Part 3
Understanding Validation and Technical Transfer, Part 3
Validation ensures safe and effective biologic products that benefit the patients whose health and wellbeing depend on the therapies. Part 1 |…
Article
Continuous Manufacturing: A Changing Processing Paradigm
Case studies with mAbs have shown similar yield and purity compared with batch runs and could be associated with an increase in productivity, they note. Other advantages of continuous manufacturing in…
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
The wide availability of scale-down models for suspension processes, such as the ambr platform from Sartorius, also allow for process intensification to increase vector productivity to comparable leve…
Article
Aseptic Processing: Keeping it Safe
By Randi Hernandez, BioPharm International
Humans represent the greatest risk for microbial contamination in an aseptic process.
Aseptic processing has garnered some increased scrutiny…