Search results for " future"
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Process Chromatography: Continuous Optimization
“We believe that both binding capacities and chemical resistance can be further improved for future protein A resins,” he observes.
Growing diversity
The increased diversity of pipeline therapeuti…
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The New World of Biopharmaceutical Manufacturing
Industry experts discuss the single-use revolution and changes to upstream and downstream processing equipment.
By Jennifer Markarian
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Unifying Continuous Biomanufacturing Operations
In the future, manufacturers will still have to identify optimal cycle time; weigh the risk of scale-up and explore how to construct continuous models that could eliminate scale-up altogether; test th…
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Witnessing Major Growth in Next-Generation Antibodies
Including next-gen antibodies in pharma pipelines is considered essential for future success.
By Cynthia A. Challener
Next-generation antibodies are designed to be more specific and are ofte…
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Automating Bioprocesses
Automation of stainless-steel systems and single-use systems differs in complexity.
By Jennifer Markarian
Both upstream and downstream biopharmaceutical processes have conventionally used st…
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Automating Processes in Upstream Processing
…h and then trying to provide the agility within the software to cope with the process changes in the future. Customers are looking for new product introductions (NPIs) to take place in their faciliti…
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Improving Process-Scale Chromatography
In the immediate future, downstream bioprocessing will likely involve hybrid solutions with both single-use and stainless-steel equipment and limited linkage of unit operations.
While there are no…
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Efforts Accelerate to Streamline Postapproval Change Process
Another FDA guidance, published in April 2016, encourages manufacturers to utilize comparability protocols, also known as PACMPs in the European Union, to outline planned future changes and how they w…
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Mixing dynamics in a large volume single use mixer
Dissolution studies will be used in the future to understand the liquid-liquid and powder-liquid mixing times along with zone mapping and test validation.
Download the application note.
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Downstream Processing Continues to Worry CMOs
This could be seen as a leading indicator of future problems for biotherapeutic developers, whose problems are gradually increasing in their own right.
CMOs are trying out various approaches to …