Search results for "Upstream"
Article
Automated Concentration and Diafiltration of Multiple siRNA Samples
A team of scientists collaborated on a project to transfer a conventional manual concentration/diafiltration process for siRNA production.
ABSTRACT
The use of small-interf…
Resource
Guidance for Industry: Quality Considerations in Demonstrating Protein Product
FDA's guidance for Industry Quality Considerations in Demonstrating Protein Product
Resource
The Development of Therapeutic Monoclonal Antibody Products
This report provides a roadmap for the development of a monoclonal antibody product from initial discovery through the filing of an Investigational New Drug Application (IND) or Investigational Medi…
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Considerations for smarter and faster process development
What you will learn:
Industry drivers to go smarter and faster in process development
Strategies for more efficient upstream process development
Strategies for more efficient downstream proce…
Article
Free eBook: Considerations for smarter and faster process development
What you will learn:
Industry drivers to go smarter and faster in process development
Strategies for more efficient upstream process development
Strategies for more efficient down…
Article
Enhancing Resins Addresses Purification Concerns
Deorkar points out that a major challenge in rAAV purification is the removal of empty capsid particles, which is an impurity generated during upstream processing. “These empty capsids do not contain …
Article
Successful Development of Scalable AAV Processes: Part 2 of 2
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In the second of a two-part series, Anki Magnusson, Staff Research Engineer, Protein and Viral Production, and Åsa Hagner-McWhirter, PhD, Senior Scientist, Bio…
Webcast
Strategies and emerging technologies for mAb capture
Strategies will depend on the mode of upstream operations (fed batch or perfusion) and the desired process improvement of the capture step, e.g., productivity, cost, or process time, as well as the ty…
Article
Strategies and Emerging Technologies for mAb Capture
Strategies will depend on the mode of upstream operations (fed batch or perfusion) and the desired process improvement of the capture step, (e.g., productivity, cost, or process time) as well as the t…
Article
Basics in Process Development for Biotherapeutics
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Definitions, activities, and things to consider when developing an upstream or downstream bioprocess.