Search results for "analytics" in Articles / App Notes
Article
N-Glycan Analysis of Biotherapeutic Proteins
This article summarizes the approaches, challenges, and future perspectives for the characterization of N-glycans in biopharmaceutical products.
By Aled Jones
Protein glycosylation, the addi…
Article
Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
One example of how analytics come into play in biosimilar manufacturing is in the development of copies of Humira. “We have a lot of companies trying to make a biosimilar copy of that molecule. One of…
Article
Biosimilars: Making the Switch Comes with Challenges
…aking improvements at the production and preclinical stages, for example by implementing the latest analytics and other imaging technologies to detect impurities and unacceptable differences in struc…
Article
Implications of Cell Culture Conditions on Protein Glycosylation
The authors present a review of the techniques commonly used for glycosylation analysis.
By Michiel E. Ultee, PhD, Dr. Richard Easton
This article reviews the implications of cell-culture co…
Article
Detecting Protein Aggregates and Evaluating their Immunogenicity
Mar 01, 2015
By Randi Hernandez
BioPharm International
Volume 3, Issue 28
Aggregation in biopharmaceuticals remains a major concern and threatens the stability of a product. Protein …
Article
High-Throughput Process Development in an Historical Environment
About 100 delegates from 13 different countries joined the discussions on HTPD case studies in upstream, downstream, and formulations, as well as modeling, data analysis, and analytics. A new session …
Article
Predicting Progress in Protein Aggregation
Techniques to enable the design and formulation of stable, protein-based therapeutics.
In silico analysis and the evaluation of formulability, aided by new analytical tools such as hydrogen deut…
Article
A Closer Look at Affinity Ligands
Affinity ligands play an exciting role in the ever-growing sphere of downstream processing. In speaking with BioPharm International®, Phillip Elliott, PhD, associate director of Process Development,…
Article
Report from the 6th International HTPD Conference
Analytics is still a challenge in HTPD work
The challenge of having access to sufficient high-throughput analytical technologies has been a repeating topic during the HTPD conference series. Ja…
Article
Maximum Output Starts with Optimized Upstream Processing
…um and thus ultimately impacting upstream bioprocessing capacity: continuous manufacturing, process analytics, and radically improved downstream purification. “There is a real shift,” agrees Chilima,…