Search results for "purification" in Articles / App Notes
Article
Overcome Chromatography Challenges with Fiber Adsorbents
Bioprocessing evolution highlights the desire for new purification technologies that offer greater flexibility for use—from research and early process development through large-scale commercial prod…
Article
Design Considerations for a Commercial Cell and Gene Therapy Facility
Cell therapy production does not have the numerous purification steps and analytical tests that are standard to mAb production.
To be able to scale up viral vector manufacturing, bioreactors—wit…
Article
Addressing the Complex Nature of Downstream Processing with QbD
In one case, we had an engineered antibody, which possessed properties that were not entirely amenable to our platform purification process.”
The company developed a new platform process for these…
Article
Moving PAT from Concept to Reality
…uence variants; nanotechnology-based analysis of charge heterogeneity that does not require protein purification; aptamer-based biosensors for N-glycosylation evaluation; next-generation sequencing (…
Article
Fiber-Based Protein A Chromatography for HTPD
Many analyses require purified proteins, and often substantial hands-on time is required for purification. The novel cellulose fiber technology (known as Fibro) may be used with ÄKTA™ chromatogra…
Article
How To Interpret Protein Binding Capacity: Chromatography Resins
The comparison between protein binding capacities of resin from different suppliers is not always straightforward. Different methods may have to be used, and often these methods are not stated direc…
Article
Reference Guide: Empty Chromatography Columns for Lab Scale
This guide offers an overview of Cytiva's empty chromatography columns designed for use in lab scale, including:
• Main technical specifications
• Compatibility with base matrix
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Article
New Selection Guide: Ion Exchange Chromatography Columns and Resins
Use these decision trees to find the most appropriate resin for your needs.
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Article
Case Study: Process for Production of Oncolytic Adenovirus
The case study describes a process from upstream cell culture to downstream purification, using scalable modern tools and technologies.
Read the case study on "Process for Production of Oncolytic…
Article
New Guide for Packing HiScale, XK, and Tricorn Columns
This guide summarizes parameters for packing small-scale HiScale™, XK, and Tricorn™ columns with Capto and MabSelect resins from Cytiva.
Download the Packing Guide