Search results for "purification"
Article
Online Ion Exchange Chromatography (IEX) Resource Hub—All in One Place
Are you an IEX-pert? If you use ion exchange chromatography, check out Cytiva's online IEX resource hub for useful information, from fundamentals to tips for advanced practitioners.
Read more
…
Article
How Coupling MALS to IEX Can Help Protein Characterization
Coupling ion exchange chromatography (IEX) to multi-angle light scattering (MALS) can open new opportunities in protein characterization. Mario Lebendiker and Hadar Amartely from The Hebrew University…
Poster
A Scalable Adenovirus Production Process
To meet these needs, a process for adenovirus production, from upstream cell culture to downstream purification, using modern tools and technologies was developed.
The novel process is easily sc…
Article
Interpreting Protein Binding Capacities for Chromatography Resins
Click here to read more >>
Comparing the protein-binding capacities of resins from different suppliers is not straightforward because different methods may have been used and these methods are n…
Article
Understanding Validation and Technical Transfer, Part 3
Any purification procedures and processes, such as recrystallization, chromatography, and viral clearance or inactivation, should likewise be characterized and defined. Cell lines, fermentation proces…
Article
Leveraging Data for Better Biopharmaceutical Process Control
This is true upstream, but we’re also seeing more advanced control move downstream to help better control yields and purification steps, and even to improve the management of plant and equipment.
…
Article
Single-Use Chromatography: Adapting to Manufacturing Scale
…cusses strategies for meeting the ever-increasing upstream titers and volumes to prevent downstream purification from becoming a bottleneck.
Learn more here
Article
Efficient Cleaning-In-Place Methods for Protein-Based Antibody Affinity Chromatography Resins
This whitepaper discusses cleaning of affinity resins intended for use in the purification of monoclonal antibodies and antibody fragments, for example, Fab fragments. Various cleaning strategies and …
Article
Exotoxin Clearance from mAb Samples in a Two-Step Chromatography Process
A heat-stable exotoxin can remain as a contaminant of a drug substance throughout the whole manufacturing process, with the risk of adversely affecting patients’ health. One such toxin is cereulide …
Article
Process Development: What May Lie Ahead in 2018?
…
·
Avoiding Investigational Failures and Discrepancies
·
High Throughput Protein Purification at a Glance
·
Top Trends in Biopharmaceutical Manufacturing, 2017