Search results for " fluid" in Articles / App Notes
Article
Sterilization Trends for Single-Use Consumables
VHP is used to frequently decontaminate exterior surfaces of SU systems such as in isolators, but is not amenable for sterilization of internal fluid paths.
E-beam sterilization is another form of…
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Considerations in depth filter scale-up
The filter media thickness, pore size distribution, and adsorptive capacity make them the ‘go-to’ technology in harvest applications where a product is separated from a complex cell culture fluid.
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HTPD 2023 conference is coming up. What will be discussed and what happened last time?
We are also pleased to have Professor Martina Micheletti giving a plenary talk on the topics of bioprocess fluid dynamics.
The Organizing Committee, invite you to the 6th HTPD meeting and look fo…
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Digitalized PD: Speeding up downstream process development
Mechanistic models enable the simulation of chromatography processes based on fundamental natural laws, such as fluid dynamics and thermodynamics. In silico simulations of chromatography proce…
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Xcellerex™ X-platform bioreactor live virtual demo
In this virtual event, Ken Clapp will explain how we developed the Xcellerex™ X-platform bioreactors using a verified computational fluid dynamics model. Thomas Falkman and Sanna Tronnersjö will join …
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Accelerating VLP purification process development
In contrast, mechanistic models describe the transport of sample components using fluid dynamic and thermodynamic principles. Further, they allow for efficient process optimization in silico.
R…
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Mechanistic Modeling: Current Advantages and Future Opportunities in Biopharmaceutical Process Development
Only the fluid dynamic parameters must be adapted to the new scale. The actual interactions of molecules with the ligands on the resin do not change.
In summary, I am convinced that soon, modelin…
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Eliminating Residual Impurities Starts with a Strategic Plan
Chandrasekaran notes that most conventional detectors lack the sensitivity to accurately measure residual impurities in process fluids. “Developing a non-denaturing method is critical to avoid inaccur…
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Biomanufacturing: Demand for Continuous Bioprocessing Increasing
The classic and still predominant approach to bioprocessing, both upstream and downstream, remains batch processing, with manufacturing batch fluids essentially moving incrementally en-masse from one …
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Cell-Culture Advances Test Bioreactor Performance Models
In particular, the inexpensive computing power and excellent computational talent entering the biopharma industry, combined with improvements in computational fluid dynamics (CFD) and metabolic modeli…