Search results for " continuous"
Article
A Platform Approach for the Identity Testing of Multi-Component Cell-Culture Media
The approach also certifies quality of media in addition to tests provided on a vendor’s certificate of analysis (CoA) by continuously evaluating cell-culture media properties during release testing. …
Article
Antibody Production in Microbial Hosts
The authors review the status of expression of antibodies in microbial hosts and present the recent advances in the production of aglycosylated antibodies in bacteria.
By Anurag S. Rathore, Jyot…
Article
Selecting the Right Viral Clearance Technology
By Cynthia Challener, PhD
The introduction of adventitious viral agents is a recognized, inherent risk of biologic drug production that is well addressed by international regulatory requirements…
Article
A Q&A With Günter Jagschies: Recovery of Biological Products Conference Series
… will then involve everyone in the audience and lead into a lively, maybe controversial debate about continuous processing, alternative or disruptive technology, and the use of modelling approaches. …
Article
Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
The readout is continuous, which allows for the quality control of the entire binding event and provides opportunities for data analysis based on binding responses obtained at one or several specific …
Article
CMOs Concerned With Cost of Single-Use Equipment
Suppliers indicate prices for single-use equipment are likely to increase.
By Eric Langer
Contract manufacturing organizations (CMOs) have been enthusiastic adopters of single-use technologi…
Article
Best Practices in Qualification of Single-Use Systems
The author discusses the current best practices in technical qualification of single-use systems.
By Weibing Ding, PhD
Single-use technology has been around for approximately two decades if …
Article
Selecting a Comprehensive Bioburden Reduction Plan
Process maps and risk assessments are among the valuable tools operators can apply to reduce the risk of microbial contamination.
By Randi Hernandez
There are multiple variables to consider …
Article
Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
By transferring a continuous gradient elution to a step gradient elution, for example, there is a significant decrease in elution volume, which shortens cycle time and increases productivity.
Conc…
Article
Taking a “Development-by-Design” Approach to Cell Therapies
Jun 15, 2015
By Agnes Shanley
BioPharm International eBooks
Volume 28, Issue 13
Whether outsourcing or developing cell therapies in-house, success demands a focus on quality, c…