Search results for " continuous"
Article
The Development and Application of a Monoclonal Antibody Purification Platform
During scale-up, we noted that effective filtration required a much larger membrane area than was feasible, so we introduced a continuous flow centrifugation process, followed by depth filtration to m…
Article
Innovations in Perfusion Bioprocessing
Furthermore, we illustrate the successful transfer of the developed perfusion process from small-scale applications to an integrated continuous bioprocess at a 50 L pilot scale
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Article
Top Tips for Successful Development of Antibody Chromatography Processes
In this interview, Jakob Liderfelt, Product Manager at Cytiva, discusses main challenges faced during chromatography process development for mAbs and mAb variants such as fragments and bispecific a…
Article
Boosting biopharma resilience: The need to shift focus and increase collaboration
Biopharma Resilience is declining. The 2023 Global Biopharma Resilience Index from Cytiva offers insights into the current state of the industry, shining a light on both areas of strength an…
Article
Report from the 6th International HTPD Conference
The biggest challenge is still the people and Quantitative Structure-Activity Relationship (QSAR) plus mechanistic modeling were two key take-home messages from the 6th International conference devote…
Webcast
Biotech Makers: Solving challenges in process development of a diversifying antibody pipeline
The therapeutic pipeline for antibodies continues to diversify into new modalities including bi-specific, tri-specific, antibody fragments and domain antibodies which bring new challenges to process…
Article
Weighing the Benefits of Single-Use Consumables
While the debate between stainless steel and single-use systems (SUS) will continue to rage for the foreseeable future, most would agree that there is a time and place for either approach. Nat…
Article
Pushing the Barriers in Next-Gen Antibody Development
Continued development of new and next-generation antibodies is spurred by the increasing demand for more effective and custom-tailored biologic therapies. In particular, bispecific antibodi…
Webcast
High-Throughput Process Development Conference 2023
We are pleased to announce the 6th International Conference devoted to High-Throughput Process Development (HTPD) and smart PD, to be held October 30-November 2, 2023 in Valetta, Malta.
The HTPD …
Article
Accelerating time to market through process innovation
Topics include:
- Next generation upstream process enablers
- Developing continuous downstream processing
- Aseptic filling
View the agenda and register here