Search results for " continuous"

Article An Integrated Approach to Ensure the Viral Safety of Biotherapeutics
By Mark Plavsic Use of continuous cell lines in the manufacture of biological therapeutic products, such as vaccines, recombinant proteins, and monoclonal antibodies, is associated with the concom…

Article Vaccine Development Faces Urgency and Challenges
Global outbreaks energize vaccine R&D and drive production modernization. By Jill Wechsler The Ebola outbreak in 2015 and the current stampede to develop a new vaccine to combat the Zika vir…

Article Fluid Handling in Biopharma Facilities
Recent advances in continuous processing promise to simplify fluid transport to a degree, while facility design also plays a large role in determining how this is performed. From a practical perspecti…

Article Using Single-Use Technologies in Downstream Processing
The use of single-use systems in downstream processing offers benefits in filtration and sampling and may reduce the risk of contamination. Jul 01, 2015 By Susan Haigney BioPharm Inter…

Article Use of Multivariate Data Analysis in Bioprocessing
Apr 06, 2015 By Anurag S. Rathore, Sumit K. Singh BioPharm International The ever increasing demand of biotherapeutics, together with the pressure to contain healthcare costs have motiva…

Article Re-use of Protein A Resin: Fouling and Economics
In view of this, there is a need to continuously monitor performance of a chromatography column during manufacturing so as to be able to anticipate any performance gaps and take appropriate action to …

Article Vaccine Development and Production Challenges Manufacturers
Mar 01, 2015 By Jill Wechsler BioPharm International Volume 3, Issue 28 Vaccines are front-page news these days. Researchers are advancing new vaccines for Ebola and other devastating di…

Article SEC in the Modern Downstream Purification Process
Mar 01, 2015 By R. Christopher Manzari, J. Kevin O'Donnell BioPharm International Volume 3, Issue 28 Since the introduction of commercial chromatography resins approximately six de…

Article Labeling of Biosimilars
EMA is under pressure to exert even tighter standards on biosimilars being marketed in Europe. Feb 01, 2015 By Sean Milmo BioPharm International The European Medicines Agency (EMA) has r…

Article Optimizing Resin Performance with Disposable Chromatography Solutions
There have not been any major technical changes in the chromatography systems or columns design; however, we are seeing continuous improvement in associated sensor performance, accuracy, reliability, …

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