Search results for " system" in Articles / App Notes
Article
Securing the Single-Use Supply Chain
Single-use systems (SUS) have become established in biopharmaceutical drug development. As confidence in the technology has increased, the adoption of disposable equipment for commercial manufacturing…
Article
Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Solid or hydrated buffers and salts that come ready-to-dispense in single-use bags and buffer preparation using single-use systems, reactors, and in-line dilution can both help eliminate or reduce wei…
Article
Gene Therapies Push Viral Vector Production
The viral-vector mechanism
Viral vector systems are gutted viruses where the packaging signals (e.g., the genetic signals that target the wrapping into the viral particles) are fused to the genes …
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Continuous Manufacturing: A Changing Processing Paradigm
To take regular samples, a robust in-line monitoring system linked to feedback and feedforward controllers is necessary, points out Sinclair. Traditional sampling and offline testing typically done fo…
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Single-Use for Downstream Chromatography: Benefit or Hindrance?
“There are very few DSP unit operations that are not using single-use systems or components,” notes Donald Young, senior global product manager, Thermo Fisher Scientific, BioProduction Division. “Clar…
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Automating the Biomanufacturing Process
Automation implementation
For more than 15 years, biopharmaceutical manufacturers have been implementing automation and control systems, both upstream and downstream, says Christoph Lebl, head of …
Article
Using Single-Use Technologies in Downstream Processing
Jul 01, 2015
By Susan Haigney
BioPharm International
Volume 28, Issue 7, pg 24–26
The use of single-use systems (SUS) in biopharmaceutical manufacturing has been steadily increasing. W…
Article
How To Execute Successful Data Migrations
By Art Meisler
Data migration is the unglamorous task of a system implementation. And so, life-sciences companies often give short shrift to data migrations in comparison to new or upgraded …
Article
Fluid Handling in Biopharma Facilities
Facility layout can help determine how companies handle fluid transfer and storage, and increased use of modular facilities and single-use systems (SUS) in the production and transfer of sterile fluid…
Article
Achieving Process Balance with Perfusion Bioreactors
While the implications of media consumption from an economic perspective can be determined at small-scale rather effectively, it is in the scale-up phase where the system design is imperative for real…