Search results for " system" in Articles / App Notes
Article
Design Considerations for a Commercial Cell and Gene Therapy Facility
For mAb bioprocessing and viral-vector manufacturing, the equipment needed is similar, such as single-use bioreactors and standard harvest and downstream systems for clarification, tangential flow fil…
Article
State of the Biopharmaceutical Industry: Lessons from 2018 Survey Data
Strong desires and perceived needs for improved single-use systems continue, despite this equipment now being available for over a decade and having come to thoroughly dominate pre-commercial manufact…
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Optimizing Late-Stage and Commercial Cell-Culture Processes
Other innovations, such as culture miniaturization with representative systems, permits testing of many culture conditions in a short period of time. In addition, development of intensified processes …
Article
Process Chromatography Selection for Downstream Processing Applications
Other simplifications are single-use systems where critical systems components (columns, flow kit etc.) are used for one campaign only, omitting the cleaning steps and the need for cleaning validation…
Article
Technologies and Practices Must Evolve to Meet Demand
Chromatography systems, filtration, and centrifuges received marks of “excellent” from more than 20% of the respondents (Table I). Sampling systems, single-use systems, and sterile sampling received “…
Article
2014 Manufacturing Trends and Outlook
In a recent survey of current trends and practices in biopharmaceutical manufacturing, BioPharm International readers revealed a preference for disposable systems, identified challenges for different …
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Navigating Emerging Markets: Middle East and North Africa
In fact, the region known as the Middle East contains a mixture of countries with significant differences in wealth, standard of living, and healthcare system sophistication. The region, however, does…
Article
Stirring up the fermentation game
Both the achieved microbe densities and product yield were shown to be consistent with the performance of conventional stainless steel systems.
Fig 1. XDR-50 MO fermentor vessel and I/O cab…
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Milestones and Moderate Progress in 2012 Drug Approvals
coli, two in yeast-based systems (one each in S. cerevisiae and P. pastoris), and one product is produced in an engineered plant-based system. These figures once again reflect the ongoing dominance of…
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Virus-like Particles as Therapeutic Moieties of the Future
At least 110 VLPs have been constructed so far from 30 different virus families (1), and a variety of expression systems ranging from bacteria to mammalian cell systems have been used for their produc…