Search results for "cleaning" in Articles / App Notes
Article
Tools for Continuous Bioprocessing Development
The form factor of the microbioreactor also enables integration of a perfusion filter membrane directly inside the growth chamber, where constant mixing of the culture provides passive filter cleaning…
Article
CMOs Concerned With Cost of Single-Use Equipment
Suppliers indicate prices for single-use equipment are likely to increase.
By Eric Langer
Contract manufacturing organizations (CMOs) have been enthusiastic adopters of single-use technologi…
Article
Best Practices in Qualification of Single-Use Systems
Article
Continuous Chromatography: Trends, Definitions and Approaches
Process Development Forum speaks with Karol Lacki, Customer Collaborations Leader at Cytiva, about continuous chromatography.
There is a lot of attention being paid to continuous chromat…
Article
Implementation of Raw Material Control Strategies in the Manufacture of Single-Use Bioprocessing Containers
The use of disposable equipment in the biopharmaceutical industry is rapidly increasing, as it offers advantages in terms of flexibility, elimination of cleaning procedures, and reduced capital expend…
Article
Challenges and Trends in Biopharma Facility Design
Experts discuss the future of modular manufacturing and the challenges that biopharma manufacturers face in facility design.
Sep 1, 2014
By: Susan Haigney
BioPharm International
Volu…
Article
Determining Criticality-Process Parameters and Quality Attributes Part I: Criticality as a Continuum
• Parameters for sterilization processes and cleaning process and the preparation of process intermediates can be included in the primary process assessment. Alternatively, they can be treated as inde…
Article
Trends in Downstream Bioprocessing
…ography materials
• Lack of single-use (disposable) options
• Cost of membranes
• Cleaning and validation costs
• Time for operations.
In addition, while many firms would like to …
Article
The use of Xcellerex™ mixing system as slurry tank when packing chromatography columns
The single-use system eliminates the hassle of time-consuming and costly steamin-place, clean-in-place, and cleaning validation procedures. The result is an efficient processing and rapid batch-to-ba…
Article
The Development and Application of a Monoclonal Antibody Purification Platform
…urities such as DNA and some HCPs were captured on the resin (and later removed by regeneration and cleaning steps). After anion exchange, the flow-through fraction containing the antibody was passed…