Search results for "cleaning" in Articles / App Notes
Article
Achieving Process Balance with Perfusion Bioreactors
“Users can eliminate most of the cleaning and validation steps that are associated with stainless-steel systems, saving both time and cost. They can also realize economic benefits with the reduction o…
Article
Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
Bioprocessing lines/facilities need some downtime, including for switchovers, maintenance, new equipment installation and validation, staff training, and cleaning and sterilization of stainless steel …
Article
Understanding Validation and Technical Transfer, Part 3
Any cleaning and sterilization procedures can likewise be specified and validated.
The cell isolation process can be validated for the particular type of cells that are collected, including stu…
Article
Putting Viral Clearance Capabilities to the Test
“In addition, expanded ranges of critical operating parameters may be evaluated, and column cleaning and carry-over must be evaluated.”
In testing prior to Phase III, Gilljam notes, “Reduction of …
Article
Chromatography Scale-Up: Don’t Get Tied Down by Bed Height
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When scaling, you can make better use of existing chromatography columns while avoiding overcapacity.
Keeping a constant residence time is a well-est…
Article
Making the Move to Continuous Chromatography
Making the Move to Continuous Chromatography
Early adopters are benefiting from lower costs and increased productivity.
By Cynthia A. Challener
Tashatuvango/Shu…
Article
Development and Future of Protein A Chromatography Technology: Q&A with Jonathan Royce, Business Leader Chromatography Resins, Cytiva
Although Protein A resins introduced to the market in the last 10 years withstand low to medium concentrations of sodium hydroxide for cleaning, like 0.1 M sodium hydroxide and in some cases 0.5 M, th…
Article
Speed and Flexibility Are Dual Goals for Biopharma Operations
In addition, biopharma companies and contract manufacturers seek the flexibility to produce multiple products on a single line with minimal downtime for cleaning and changeover.
Modular processing…
Article
Accelerated flavivirus vaccine production with modern tools and solutions
…t increased operator safety, while reducing time to market by eliminating costly and time-consuming cleaning operations. By allowing for quick startup and changeover between productions, single-use t…
Article
Automating Bioprocesses
…quipment systems, which saves initial capital costs and the ongoing production time associated with cleaning and sterilization. The process control and automation requirements of SUS also differ from…