Search results for " cost"
Article
Viral Clearance Challenges in Bioprocessing
Minimizing manufacturing cost
As purification templates are established, the cost of goods is of particular importance because there is often pressure to limit operations to those that are necessar…
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Monoclonal Antibodies Key to Unlocking the Biosimilars Market
mAbs are also extremely costly, and biologic versions are needed to maintain functioning healthcare systems, according to Theodor Dingermann, a professor and director of the Department of Pharmaceutic…
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Implementing QbD in Sterile Manufacturing
… In our experience, the main challenges in applying a QbD approach are due to the intensity of time, cost, and resources in the early-development stage. Another significant challenge is the high degr…
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Quality by Design: A CMO's Perspective on Gaining Knowledge Faster and Better
…ent and characterization may increase and many experiments must be repeated, adding to timelines and cost. Thus, by not following a well-defined development plan up front (i.e., a quality-by-design […
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Evaluating the Use of Continuous Chromatography
In addition, continuous processing intensifies production and lowers capital costs, while enabling better control (1).
Although significant strides have been made to advance continuous upstream pr…
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Maximum Output Starts with Optimized Upstream Processing
Selexis and KBI Biopharma, for instance, have invested in technology and innovation in cell-line development and process development to reduce cost of goods while increasing output at a given scale. H…
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Innovative Chromatography Resins Can Improve Purity and Quality
Development of an individual, multi-step chromatography downstream processing (DSP) for every recombinant protein anew increases overall development costs and timelines, and hence prolongs time-to-mar…
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Remote Monitoring and Big Data Advance Upstream Automation
… products to be scaled up or scaled out more rapidly and thus launched more quickly with predictable cost, quality, and schedule, according to Sandusky. “Hardware advances give the opportunity for hi…
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How To Execute Successful Data Migrations
Like business applications, successful migrations must be measured by the extent to which they meet the business needs in a timely, cost-effective manner that attain the highest level of data integrit…
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Next Generation Process Chromatography
If we consider highly efficient multi-tonne processes like the blockbusters of today, then the cost of goods of the process and facility output are already highly efficient. The cost efficiency of mAb…