Search results for " biotherapeutic" in Articles / App Notes

Article Videos! SPR Applications in Protein Characterization
In these exclusive videos from the Biacore Analytical, Comparability and QC Symposium, Vienna, November 2017, industry thought-leaders share insights, tips, and techniques that illuminate how SPR with…

Article Sensitive and Reproducible SPR-Based Concentration and Ligand-Binding Analyses
This article focuses on concentration assays associated with late-stage development and biotherapeutic drug chemical manufacturing and control. Read the article here.

Article The Challenge of Disruptive Technologies in Bioprocessing
Because product yield drives the cost of goods (COG), not having an affinity purification solution can significantly impact the COG for biotherapeutic manufacturing, she says. “The Thermo Scien…

Article Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
The quantitative trend analysis provides details and comparisons of production by biotherapeutic developers and CMOs. It also evaluates trends over time and assesses differences in the major markets i…

Article Biopharmaceutical Market in Asia: Q&A with Günter Jagschies, Strategic Customer Relations Leader, Cytiva
Asia has a complex mix of economies from low to high income with a largely varying degree of access for the population to biotherapeutic drugs on the high end of the price range as well as even to the…

Article QbD Improves Cell-Culture Process Control
Mammalian cells are most frequently used as the hosts for manufacturing complex biopharmaceuticals, and cultivation of these host cells is a key factor in the production of biotherapeutics. The cultiv…

Article Process Chromatography: Continuous Optimization
Yield drives cost of goods (COG), so not having an affinity purification solution can greatly impact the COG for biotherapeutic manufacturing,” Terova explains. With the increase in more challengi…

Article The New World of Biopharmaceutical Manufacturing
That technology has grown in sophistication and scale required to produce large scale quantities of biotherapeutics (up to tons/year) and vaccines (hundreds of millions of doses/year). Steam-in-place …

Article Witnessing Major Growth in Next-Generation Antibodies
“Hence, next-generation biotherapeutic technologies have potential in virtually all human diseases,” Chan asserts. Real advantages These new antibody formats are attracting attention because t…

Article Mechanistic Modeling of Preparative Ion-Exchange Chromatography
Ion-exchange chromatography (IEC) is a major workhorse for purification of biotherapeutics. Development of a mechanistic model requires three major steps: modeling of mass transfer, modeling of bindin…

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