Search results for " development" in Articles / App Notes
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Cell culture process development for AAV vector production in suspension cells
Adaptation of HEK293 suspension cell line for transient transfection and scalable adeno-associated virus (AAV) production.
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Digital transformation of biopharmaceutical process development
Digital transformation has become an increasingly important topic for the biopharmaceutical industry as it leads to new opportunities for additional value creation and competitiv…
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Virtual Scientific Symposium: Process Development: Go Smarter, Go Faster!
In this free virtual symposium, you'll hear from leaders at GlaxoSmithKline, Byondis, UCB, UCL, GoSilico, and Cytiva on how they balance innovation, speed, and robustness to accelerate their process d…
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Basics in Process Development for Biotherapeutics
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Definitions, activities, and things to consider when developing an upstream or downstream bioprocess.
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Selecting Chromatography Formats for Your Process Development Workflow
The quality-by-design initiative by the FDA puts additional demands on process development work because a higher degree of process understanding is needed.
Therefore, the choice of tools is critic…
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Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
By Anna Grönberg
An important area of focus for the biopharma industry is the elucidation and development of robust, efficient, and economic purification strategies for new monoclonal antibodies (…
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What Drove Biopharma Development in 2014?
As federal agencies continue to push for proof of quality in biologics, there is increased interest in, and use of, QbD in pharmaceutical development and that trend is only expected to rise. According…
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Mechanistic Modeling: Does it Have a Future in Process Development?
Novo Nordisk uses mechanistic models for the development of selected downstream process steps. Following his keynote presentation to attendees at the recent HTPD Conference in Italy, Arne Staby, PhD, …
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EMA Invites Comments on New Guidance for Vaccine Development
The guidance covers the non-clinical and clinical requirements for the development of new influenza vaccines and aims to facilitate the prompt assessment of new vaccines. It follows the publication of…
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Insights from process developers - top challenges in recombinant protein purification
This constantly evolving molecular diversity brings challenges in chromatography process development. In this article, we focus on the challenges in purifying recombinant proteins that lack affinity c…