Search results for " binding" in Articles / App Notes
Article
Chromatography innovations for the diversified antibody pipeline
Our MabSelect™ VH3 affinity resin interacts with the variable heavy chain of the VH3 sequence family of human antibody, delivering high binding capacity and efficient separation of product-related imp…
Article
Video: Standardize recombinant protein purification process development
This technology standardizes purification during process development of any protein that does not have an affinity binding partner.
WATCH THIS VIDEO TO LEARN MORE
Article
Report from the 6th International HTPD Conference
Calculated descriptors for proteins and resins could then provide predictions of product binding and optimal screening regions for separation. This QSAR models were followed by the mechanistic modelin…
Article
Balancing AAVs Versus LLVs
Knowledge of adeno-associated variant's infection pathway is based on only a few serotypes. The prevailing understanding is that serotypes bind to different, or have differential affiniti…
Article
Get more from UNICORN™ software with plug-in extensions
Access extensions for UNICORN software from the new Cytiva Marketplace, including a free extension that performs Dynamic Binding Capacity (DBC) calculations for breakthrough volume and QB valu…
Article
Optimization of a two-step purification method for bispecific antibodies
Bispecific antibodies (bsAbs) have gained increasing interest over recent years because they can bind two antigens, offering unique modes of action compared to monoclonal antibodies. New and i…
Article
Download your Mechanistic Modeling eBook
It also uses adsorption isotherms to quantify how molecules compete for ligands when binding.
Why use mechanistic modeling in downstream process development?
With mechanistic models, proc…
Article
Get to know: mAb variants - eLearning
Key learnings are:
- Structure and binding domains for antibody variants
- Advantages and disadvantages of different antibody fragments
- Design strategies for bispecific antibodies (bsAbs)
…
Article
Finding the Needle in a High-Dimensional, Information-Rich Data Haystack Can Be Time Consuming
With these tools, scientists can detect and characterize low molecular weight and low affinity compounds binding to their targets.
Improvements in data analysis software have helped to streamline …
Article
Virus-like Particles as Therapeutic Moieties of the Future
Functional analysis
Functional characterization of VLPs includes assays to evaluate binding ability of drug delivery vehicles to specific target cells, or antigenicity and immunogenicity of vaccin…