Search results for "analysis" in Articles / App Notes
Article
Technology Innovations Improve Process Chromatography Performance
Deorkar adds that finding efficiencies and economies of scale in downstream processing involves more complex analysis and optimization. Improvements may be reached after investigating aspects of curre…
Article
Eliminating Residual Impurities Starts with a Strategic Plan
The chosen separation and detection technologies must also be suitable to the analysis without degradation of the impurities occurring.
Overall, potential process-related and other residual impu…
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The Importance of Partnering for Bioanalytical Studies
Additional information, such as incurred sample reanalysis results and sample condition (e.g., hemolyzed) may also be included.
Bose (Emery Pharma): On a broader perspective, FDA requires PK, to…
Article
Gene Therapies Push Viral Vector Production
The potential opportunity of a vector depends on the type of gene therapy being developed, says Gaurav Chaudhary, CEO of Roots Analysis, a business research and consulting firm. In general, there are …
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Best Practices for Selecting a Top-Quality Cell Line
Two specific challenges, Cai continues, include clippings for bispecific antibody and fusion proteins, which may require many constructs screening and extensive mass analysis or peptide mapping to det…
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Western Blot Detection: Is Film or a Digital CCD Imager Better?
Western blotting, known also as immunoblotting or protein blotting, is a well-established and widely accepted form of protein detection and analysis. It is based on building an antibody:protein comple…
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A Look at the Affinity Chromatography Landscape
Affinity chromatography is also being used for the analysis of viral vectors, according to Thom. Specially designed kits specific for lenti- or adeno-virus count total viral particle load in rapid, no…
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Achieving Process Balance with Perfusion Bioreactors
Off-gas analysis (O2/CO2) is now also used in cell culture to calculate metabolic flux. “Multivariate data analysis (MVDA) using software such as our SIMCA online system allows efficient process contr…
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Ensuring Viral Safety of Viral Vaccines and Vectors
Extraneous vesiviruses, however, have recently appeared in bioreactors (2–5), and porcine circovirus type 1 (PCV-1) contamination of oral rotavirus vaccines was first reported by a metagenomics analys…
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The Challenge of Disruptive Technologies in Bioprocessing
“Advanced automation also involves the use of trend analysis and correlations between ‘simple’ measurements and ‘complex’ quality attributes,” he says.
“This all helps to lower the cost of the …