Search results for "regulatory" in Articles / App Notes

Article CMOs Continue to Improve Overall Biomanufacturing Performance
Better process development is creating industry benchmarks for bioprocessing. By Eric Langer Biomanufacturing efficiency is on everyone’s minds, being the single most important area of focus…

Article Capto™ Core 700 in Vaccine Processing
The aim with this white paper is to discuss the advantages of using Capto Core 700 in virus purification compared to size exclusion chromatography (SEC), a technique commonly used in several vaccine…

Article The Metrics of Quality Culture
FDA’s proposed guidance for quality metrics raises questions about quantifying the tangibles and intangibles of quality culture. By Andrew Harrison, Susan J. Schniepp The long awaited, anxio…

Article CMOs Concerned With Cost of Single-Use Equipment
…s and loss of production material is a concern” (19% of biotherapeutic developers) • “For regulatory reasons, we can’t change our current systems” (15.5%). For CMOs, however, the top reasons …

Article Selecting a Comprehensive Bioburden Reduction Plan
Process maps and risk assessments are among the valuable tools operators can apply to reduce the risk of microbial contamination. By Randi Hernandez There are multiple variables to consider …

Article Breakthrough Drugs Raise Development and Production Challenges
Manufacturers and FDA look for innovative strategies to meet accelerated timeframes. Jul 01, 2015 By Jill Wechsler BioPharm International Volume 28, Issue 7, pg 8–9 The FDA pro…

Article Advanced Technologies Facilitate Scale-up and Technology Transfer
Single-use and modular technologies plus continuous manufacturing are increasingly important to biopharma scale-up and tech transfer. Jun 01, 2015 By Cynthia A. Challener BioPharm Inte…

Article Vaccine Development and Production Challenges Manufacturers
Mar 01, 2015 By Jill Wechsler BioPharm International Volume 3, Issue 28 Vaccines are front-page news these days. Researchers are advancing new vaccines for Ebola and other devastating di…

Article Quality by Design and Extractable and Leachable Testing
The author discusses the various ways in which a quality-by-design program can enhance the extractable and leachable assessment of a drug product. Feb 01, 2015 By Anthony Grilli BioPharm…

Article Fermentation for the Future
Improving efficiency, value chain, quality, and protein complexity with advanced bioprocess development. Jan 01, 2015 By Cynthia Challener, PhD Microorganisms—bacteria and yeast—have b…

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