Search results for " scale up"
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Concentrating Feed—an Applicable Approach to Improve Antibody Production
In this study, the authors evaluated different approaches to prepare highly concentrated feed media for fed-batch Chinese hamster ovary cell culture. By raising the pH or by adding surfactants, the fe…
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Overview of a scale-up of a cell-based influenza virus production process using ReadyToProcess equipment
Sufficient cell recoveries were obtained for a split ratio of 1:5 during scale up from 10 L to 50 L working volume.
A common challenge upon cell transfer is the lag phase, during which the cells…
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A Closer Look at Affinity Ligands
Affinity ligands play an exciting role in the ever-growing sphere of downstream processing. In speaking with BioPharm International®, Phillip Elliott, PhD, associate director of Process Development,…
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Video: The solution to smarter column packing
Packing modern chromatography resins at large scale requires a column capable of axial compression to ensure stable, reproducible packed beds. AxiChrom™ columns are low-pressure, axial compressi…
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A Look into Biologic Scale-Up Strategies
Yet, despite decades of process optimization, there remain stubborn challenges—or new challenges that have arisen–during the scale up of cell culture processes.
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Better bioprocess scaleup with Bioreactor Scaler Pro
Are you still using the manual input, trial-and-error method when scaling your cell culture process, spending long hours in the lab analyzing uncertain data?
With Bioreactor Scaler Pr…
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Chromatography for the Diversified Antibody Pipeline
CytivaVideo
In this video, Eva Heldin, Section Manager of Antibody Application in R&D at Cytiva is interviewed by BioPharm International and shares what antibody therapies are in the pipelin…
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Evolving demands of process development services
Shifting demands from industry innovators is leading to an increased need for flexible and agile outsourcing partners offering broad and integrated models.
Over the years and in light o…
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COVID-19 Diagnostics Supplier Ramps Up Production with Help of Cytiva’s Testa Center in Sweden
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In this blog post, you can learn about how Solis BioDyne, Estonian manufacturer of polymerase chain reaction/quantitative polymerase chain reaction reagents to analyze DNA f…
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Mechanistic Modeling: Theory to Implementation
Is your downstream process development workflow relying on experimental data alone, or are you leveraging mechanistic modeling? Gain a better understanding of effective modeling implementation to deve…