Search results for " therapeutic"
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Biopharma in 2015: A Year for Approvals and Innovations
While the US has approved only one biosimilar therapeutic; Japan, Australia and Europe have approved six, eight and 19 biosimilars respectively. Biosimilars have an exemplary safety track record in th…
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Modular Manufacturing Platforms for Biologics
Caliber Therapeutics, originally a subsidiary of G-CON, LLC until the formation of G-CON Manufacturing Inc. in 2014, was established with Defense Department funding from the Defense Advanced Research …
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Re-use of Protein A Resin: Fouling and Economics
Thus, Protein A is considered to be the most crucial step in the purification process and a major contributor towards achieving the stringent purity levels expected of biotech therapeutics with HCPs r…
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USP Publishes Monoclonal Antibody Guidelines
USP standards for mAbs
Currently, licensed monoclonal antibody (mAb) therapeutics include those involved in the activation of effector cells, cell killing, cross-linked induced apoptosis, antagonis…
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Ligand-Binding Assays and the Determination of Biosimilarity
Ligand-binding assays are of great importance for the analysis and comparison of the originator and biosimilar therapeutic for both testing of the drug before administration to preclinical or clinical…
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Monoclonal Antibodies Key to Unlocking the Biosimilars Market
However, countless patients around the world do not have access to these state-of-the-art therapeutics due to their high price. Celltrion’s goal is to make antibodies more affordable to patients throu…
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Evaluating the Use of Continuous Chromatography
In downstream processing, continuous chromatography is gaining traction in the purification of protein therapeutics. As the biopharmaceutical industry strives to demonstrate, continuous manufacturing …
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Exosome isolation by tangential flow filtration and size exclusion chromatography
Acknowledgements to VivaZome Therapeutics Pty Ltd and Evox Therapeutics Ltd for contributions to this application note.
READ THE FULL APPLICATION NOTE
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The oligonucleotide synthesis process consists of a repetitive four-step cycle
The oligo therapeutics market is growing in promise for treating cancers, genetic diseases, and other conditions. In this animated video you can watch the oligonucleotide synthesis process as …
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Oligonucleotide manufacturing: how to get a strong start
Oligonucleotide therapeutics have huge potential for transforming human health. If you’re a small biotech or lab developing such therapies, playing the long game is crucial to successful in-ho…