Search results for " therapeutic"
Article
Ensuring Viral Safety of Viral Vaccines and Vectors
Moreover, conditions should be adjusted to avoid aggregation or complex formation of therapeutic viruses and, thus, product loss.
Chromatographic methods are potentially effective tools for adv…
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The Challenge of Disruptive Technologies in Bioprocessing
… processes for these new modalities, while meeting the high quality and regulatory standards for the therapeutic,” says Terova.
The biomolecule purification scheme can be very complex, particu…
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Biopharma Seeks Balance
Wessel, Emerging Therapeutic Company Investment Deals and Trends, Report, Biotechnology Innovation Organization, May 17, 2018.
Gene therapies offer the potential to …
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Establishment of New Modern Plasma Fractionation Facilities in Asia
…and Development at CSL BioPlasma, Australia, and co-author of Production of Plasma Proteins for Therapeutic Use.
Plasma fractionation is sometimes considered as a conservative industry and less …
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Industry Adoption of Single-Use Systems Remains Low
The movement away from the blockbuster drug model to more targeted therapeutics, however, is driving the need for drug manufacturers to avoid costly investments in traditionally large, stainless steel…
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Manufacturing Standards Key to Advancing Cellular and Gene Therapies
Similar issues have been discussed related to applications for Kite Pharma’s therapy for aggressive non-Hodgkin lymphoma and Spark Therapeutics’ new gene therapy to treat a rare condition causing blin…
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From Darwin to Recombinant Fc Multimers
Probably showing the complexity of the interactions, the progress towards the development of therapeutics targeting the Fc-R family for autoimmune and inflammatory diseases has been slow despit…
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Fusion Proteins Pose Manufacturability Challenges
“These molecules are of interest because the domains may have functions that, when combined, are uniquely useful as therapeutics, such as binding/inhibition of cytokines and a longer half-life,” expla…
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Being Thorough When Transferring Technology
…Biologics): The major differences in the technology transfer and process validation approach between therapeutic proteins and other small-molecule therapeutics are due to the complex nature of protei…
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Reconciling Sensor Communication Gaps
For most of the history of the biomanufacture of therapeutic proteins, in-process measurement and control focused on upstream operations. Historically, cell culture and fermentation persist longest am…