Search results for "virus" in Articles / App Notes
Article
Top Challenges to Overcome When Developing AAV Processes: Part 1 of 2
AAVprocessdevelopment
Click here to view more Industry Leader Q&As >>
In the first of a two-part series, Anki Magnusson, Staff Research Engineer, Protein and Viral Producti…
Article
How to Optimize and Scale Up AAV Production
In this article from a roundtable discussion, four experts from academia and industry met to discuss challenges in refining and scaling up AAV production pipelines to meet the increasing demand for …
Article
Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
The most common viral vectors used in gene therapy are based on adeno-associated virus (AAV) and lentivirus. However, adenovirus and retrovirus are also of interest in this space (the latter being pri…
Article
Chromatography Resin Poster for Your Lab Wall
Doing research process development on an antibody, virus, or other biomolecule? Then you’ll want this poster. It will help you quickly select the right chromatography products for your needs.
YE…
Article
EMA Guidance on Changes to COVID-19 Vaccines to Fight Variants
The European Medicines Agency (EMA) has requested that developers determine if their COVID-19 vaccines protect against new virus mutations that have been identified in the United Kingdom, South Africa…
Article
Process Development: 2020 Reflections and 2021 Possibilities
Scaling up viral vector and virus manufacturing processes prompts the need for discussion on general guidelines for how to go about the scale-up process, which was of particular interest to Bioprocess…
Article
Eliminating Residual Impurities Starts with a Strategic Plan
They can be derived from the host cell or the product itself, media components, surfactants, virus inactivation agents, inorganic or organic contaminants from permanent and single-use process equipmen…
Article
Flavivirus Vaccine: Accelerate Development and Production with Modern Tools and Solutions
This article gives an overview of modern tools and solutions, adding flexibility and speed to both upstream and downstream operations in flavivirus vaccine production.
Click here to read more >>
Article
Improving Lentiviral Vector Downstream Processing Workflows
However, these downstream workflows are long, require substantial manual labor, and suffer from low yields of infectious virus. This article discusses process development pain points of a modern workf…
Article
Manufacturing of Vaccines and Viral Vectors
In this article, general guidelines for scaling up a viral vector and virus manufacturing processes are discussed.