Search results for " Downstream PD" in Posters
Poster
Unlocking the potential for efficiency in downstream bioprocesses
In today's bioprocessing industry, there is a demand to cut manufacturing costs while maintaining product safety and quality. Additionally, flexibility needs to be increased and time to market reduc…
Poster
Integration of continuous upstream and downstream operations in mAb production
Process intensification is gaining interest as a strategy to reduce production costs, while improving product quality and throughput in the manufacturing of biopharmaceuticals. For a competitive pro…
Poster
Fast Trak Services: a collaborative project to accelerate downstream biosimilar process development
Biosimilars represent an innovative solution that can benefit both patients and healthcare systems by reducing the burden of rising treatment costs. To improve the availability, price and access of…
Poster
High-Throughput Downstream Processing Using Cellulose Fiber Chromatography and ÄKTA™ Chromatography Systems
Developing a process or looking for a clone of interest often requires screening large numbers of samples. Many analyses require purified proteins, and often substantial hands-on time is required for …
Poster
Continuous chromatography in downstream processing of a monoclonal antibody
In this study, periodic counter current (PCC) chromatography and straight-through processing (STP) technologies were evaluated in a continuous three-step monclonal antibody (MAb) purification proces…
Poster
Modes of controlling charge variant distribution in Mab production
The characteristics of a biological drug, for example, charge variant profile, are determined to a large extent by the upstream expression system and conditions, but can also be influenced by the pu…
Poster
Comparison of Three Different Screening Techniques for Predicting Step Elution Conditions for a Cation Exchanger
Screening of chromatographic conditions can be done in several ways, such as 96-well plates, mini-columns, and tips. It is important that the screening can give an indication of the optimal conditio…
Poster
A Scalable Adenovirus Production Process
The promising results from clinical studies on the use of viral vectors to address important medical needs have spurred interest in developing scalable and cost-efficient manufacturing processes. To…
Poster
A Next Generation Protein A Chromatography Resin for Improved Productivity and Bioburden Control
mAb production using a Protein A capture step has followed a highly successful synergistic path the last 30 years. There are, however, remaining challenges.
• The increased upstream titers in mA…
Poster
Case Study: Improve Process Economy by Cycling of Prepacked Chromatography Columns
The use of disposable technologies in downstream processing has increased significantly over the last years, as they reduce the need for time-consuming cleaning and cleaning validation operations as…