Search results for " Downstream PD" in Articles / App Notes

Article Developing an Efficient Adenovirus Downstream Purification Process
Adenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and adenovirus is evaluated as vaccine delivery system in many preclinical and clinical studies…

Article Full Single-Use Downstream Process? Not Any Time Soon.
Single-use technologies (SUTs) are here to stay. But where we see full single-use upstream processes, downstream is often a hybrid solution. Here’s why SUTs will not completely replace reuse systems…

Article Bioburden Entry Points in Downstream Processing
If you work in bioprocessing, you are no doubt aware of the need to prevent bioburden entry and proliferation, and reduce the complexity of the equipment and processes involved. Anastasia Lolas, for…

Article Digitalized PD: Speeding up downstream process development
Mechanistic models enable the simulation of chromatography processes based on fundamental natural laws, such as fluid dynamics and thermodynamics. In silico simulations of chromatography proce…

Article Improving Lentiviral Vector Downstream Processing Workflows
Lentiviral vectors (LVV) are a common vehicle to deliver genetic material in chimeric antigen receptor (CAR) T-cell therapy and gene therapy applications. Production methods have been developed by a…

Article Current Innovations and Practices To Address Microbial Contamination in Downstream Bioprocessing
Bioburden control is an area of serious concern for anyone making mAbs or other biologicals. Manufacturers’ efforts to avoid microbial contamination are today being complemented by development…

Article SEC in the Modern Downstream Purification Process
Mar 01, 2015 By R. Christopher Manzari, J. Kevin O'Donnell BioPharm International Volume 3, Issue 28 Since the introduction of commercial chromatography resins approximately six de…

Article Your Reliable Downstream Bioprocessing. Our Proven AxiChrom Columns
The goal for biopharmaceutical manufacturers is to develop a process that will deliver material for clinical trials quickly and smoothly, achieve success in these trials, and scale up to commercial …

Article Downstream Process Developers: What are Your Antibody Processing Challenges?
Process developers, we want to hear from you! We're asking PD scientists to tell us about their biggest challenges developing downstream processes for mAbs and their variants.  Take this …

Article Connected, Automated Downstream Process for mAb Screening and Evaluation
Click here to read more >> A pre-clinical lab is often faced with the need to constantly evaluate possible ways of increasing capacity and throughput. This study was done to show both proof of p…

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