Search results for " optimization"
Poster
Resin selection to optimize the flexural strength of bioprocess film
Single-use bioprocess technology offers several advantages for manufacturing biopharmaceuticals, such as increased transportability of fluids throughout the bioprocess workflow and a greater diversi…
Article
How to Optimize Protein Desalting
Most protein purification workflows require desalting, buffer exchange, or both at one or more steps. But how do you determine which method to use? And how do you choose the right product for your n…
Article
Optimize Column Loading Strategy to Gain Productivity in Protein Purification
Are you looking for a way to improve productivity in your affinity chromatography step? Have you ever applied the concept of variable loading to gain productivity? By varying residence time (RT) ove…
Poster
Optimizing productivity on high capacity protein A affinity medium
MabSelect SuRe™ protein A affinity medium has long been considered a starndard tool for capturing monoclonal antibodies in biopharmaceutical production. This application note summarizes studies on d…
Poster
Optimization of concentration and diafiltration of a bovine γ-globulin solution
This application note describes the development of a cross flow filtration process for concentration of a bovine
γ-globulin solution.
Article
Strategizing for Rapid Changeovers in Biologics Manufacturing
Approaches to optimizing changeovers
Strategies for optimization of process changeovers differ because the equipment and room configurations for each process are different, but all are driven by t…
Article
Platform Approach Speeds Process Development
Figure 1: Cell-culture process development concept for Phase I supply including media screening and optimization as well as bioreactor screening optimization modules. For the time scale, one box corre…
Article
Technology Innovations Improve Process Chromatography Performance
Deorkar adds that finding efficiencies and economies of scale in downstream processing involves more complex analysis and optimization. Improvements may be reached after investigating aspects of curre…
Article
Impact of Media Components on CQAs of Monoclonal Antibodies
The complexity of composition of cell-culture media offers many challenges towards optimization of the individual media components (2–3).
The formulation of optimal culture media for propagation of…
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
However, development and optimization of a process chromatography step presents a major challenge due to the large number of process parameters that can affect the performance of the step. For example…