Search results for " optimization"
Article
Q&As with Industry Leaders
…sins & Technologies at Cytiva
Cell Culture Media Considerations and Optimization for Improved Titers and Protein Quality
Peggy Lio, Senior Director of Glob…
Article
Evolution of the Monoclonal Antibody Purification Platform
As shown below, while the primary recovery module is kept as part of the flow scheme, it requires optimization to work with increased solids density, media components, and other metabolites. On the ot…
Article
State of Quality and Compliance in the Biopharmaceutical Industry
Have FDA initiatives improved manufacturing quality?
The late 1990s and early 2000s witnessed a slew of enforcement actions by FDA that included multiple Form 483 observations, warning le…
Article
Operational Excellence: More Than Just Process Improvement
By embracing efficiency and quality, biopharmaceutical organizations can work better and achieve better work.
Life-sciences companies face more pressure than ever to reduce costs and increase eff…
Article
Essentials in Establishing and Using Design Space
Set point selection and robust optimization within the design space
Once the model has been generated, optimization of all set points to find the most robust (stable) area within the design sp…
Article
Regulatory Challenges in the QbD Paradigm
The inspection team would review documents that present and justify the control and optimization of such important aspects of product quality assurance.
The emphasis of inspection would be on i…
Article
Automated Concentration and Diafiltration of Multiple siRNA Samples
A team of scientists collaborated on a project to transfer a conventional manual concentration/diafiltration process for siRNA production.
ABSTRACT
The use of small-interf…
Article
Sterilization Trends for Single-Use Consumables
Single-use (SU) technologies increasingly find use today at all phases of the drug development cycle from preclinical to commercial manufacturing. As the biopharmaceutical market continues to …
Webcast
Accelerate biotech process development
Balancing innovation, speed, and robustness to support biotherapeutic production
Biopharmaceutical process development faces new challenges: shorter time-to-market and changing regulatory expect…
Webcast
Webinar: From bottlenecks to breakthroughs: Mastering buffer management
Unlock innovation in manufacturing by optimizing your buffer production.