Search results for " modeling" in Articles / App Notes

Article Efforts Accelerate to Streamline Postapproval Change Process
Manufacturers and regulatory authorities seek coordinated lifecycle management policies. By Jill Wechsler Frequent revisions and updates in manufacturing processes and operations are routine…

Article Process Chromatography Selection for Downstream Processing Applications
Good process modeling is therefore becoming increasingly critical in order to enable accurate scenario planning and effective facility utilization. References 1. S. Haigney, BioPharm Interna…

Article Design and Qualification of Single-Use Systems
The author provides a review of the concepts of design and qualification that apply to single-use systems. By Jerold M. Martin Single-use technologies (SUT) have made significant inroads in …

Article Maximize resin usage with continuous bioprocessing
Continuous processing has proved a very successful model in many industries. As such, there has been a growing interest in using continuous concepts also in biomanufacturing. Periodic counter-…

Article Platform Approach Speeds Process Development
A modular cell-culture platform demonstrates accelerated process development. By Harald Bradl, Jan Bechmann, Benedikt Greulich, Markus Michael Mueller, Patrick Schulz, Thomas Wucherpfennig C…

Article Continuous Processing for the Production of Biopharmaceuticals
The authors review the technologies that may help bioprocessing become a truly continuous operation and present case studies that could contribute to the integration of upstream and downstream platf…

Article Framing Biopharma Success in 2016
Corporate restructurings, regulatory initiatives, and biosimilars will shape biopharma development in 2016. By Rita C. Peters The US biopharmaceutical industry turned a new page in 2015 when…

Article A Q&A With Günter Jagschies: Recovery of Biological Products Conference Series
Process Development Forum speaks with Günter Jagschies, Cytiva, who is sitting on the organizing committee for the Recovery of Biological Products XVII Conference, which will take place June 19-24, …

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
Surface plasmon resonance is helping define bispecific antibodies, the next-generation of biopharma therapeutics. By Robert Karlsson Abstract Biotherapeutic antibodies are still the larg…

Article Fluid Handling in Biopharma Facilities
Careful modeling needs to take place to ensure sufficient water for injection (WFI) is being generated by utilities and sufficient solution storage capacity is available while the process is being run…

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