Search results for " MabSelect"
Poster
Reduce Risk of Failure in Your Virus Clearance Study by Choosing Robust Scale-Down Chromatography Tools
Effective viral clearance studies remain one of the challenges facing manufacturers of biologics. These studies are an essential part of process validation and are critical to ensure drug safety. Vi…
Article
Case Study: Virus Reduction of an Affinity Capture Step
Evaluating how much a process step contributes to viral clearance is an essential part of process validation. For this reason, there is an industry need to perform effective viral clearance studies. I…
Article
New Guide for Packing HiScale, XK, and Tricorn Columns
This guide summarizes parameters for packing small-scale HiScale™, XK, and Tricorn™ columns with Capto and MabSelect resins from Cytiva.
Download the Packing Guide
Article
Single-Step, Protein A Chromatography Process for Bispecific Antibodies in Early Screening
A single-step downstream process using protein A chromatography to purify a bispecific antibody (BsAb) in early screening has been successfully developed to replace an existing three-step process. T…
Poster
High-Throughput Downstream Processing Using Cellulose Fiber Chromatography and ÄKTA™ Chromatography Systems
Developing a process or looking for a clone of interest often requires screening large numbers of samples. Many analyses require purified proteins, and often substantial hands-on time is required for …
Article
A Look at the Affinity Chromatography Landscape
A Look at the Affinity Chromatography Landscape
New ligands are being developed to meet the separation and purification needs of next-gen biologics.
By Cynthia A. Challener
…
Article
Cleaning Protein A Resins with 1 M NaOH
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For more information, visit MabSelect Protein A resins
Article
Evaluation of Performance of a Disposable mAb Affinity Chromatography Column Used Over Multiple Process Cycles
This application note demonstrates cycling of ReadyToProcess™ MabSelect SuRe™ LX columns in multiple process runs. Analysis of mAb purity and recovery as well as column bed integrity testing show that…
Poster
Columns up to 1600 mm in diameter packed with protein A chromatography medium using axial mechanical compression
This includes packing of traditional BioProcess™ media, such as the Sepharose™ family, in addition to the more modern high-flow agarose media, like Capto™ and MabSelect™ family. For most media the pac…
Poster
Purification of monoclonal antibodies using modern chromatography media and membranes
This white paper is a guide to the development of MAb purification platforms and provides an overview of Cytiva’s offering of process chromatography media (resins) and membranes for MAb purification…