Search results for " capacity" in Articles / App Notes
Article
Evolution of the Monoclonal Antibody Purification Platform
Load capacity (>1500 g/L) may be achievable with > 95% product recovery and robust process performance.
Monoclonal antibodies expressed in yeast
While mammalian cells (e.g., such …
Article
Strategizing for Rapid Changeovers in Biologics Manufacturing
Vaccine developers also need to ensure flexibility with respect to the expected required manufacturing capacity, according to Stoll. “One approach is to work with contract development and manufacturin…
Article
Gene Therapies Push Viral Vector Production
The solution to increasing viral vector capacity involves both structural and technical issues. Vicaire states that a combination of structural evolution on the CDMO side and development of new techni…
Article
Flexible Facilities for Viral Vector Manufacturing
The company has been busy expanding, and, in December 2019, it opened a 50,000-ft2 facility in Lexington, MA to provide capacity for the contract development and manufacturing organization (CDMO) to s…
Article
Supply Chain Challenges for Single-Use Systems
It is important that suppliers proactively identify the potential risks and minimize the probability and impact of supply disruptions through effective demand planning/forecasting, capacity planning, …
Article
Downstream Processing for Cell-Based Therapies
Equally, DSP techniques adapted from protein production for CGTs have the capacity to handle the scales required for allogeneic therapies but are hindered by the lack of specificity and sensitivity to…
Article
Designing a Biomanufacturing Facility Incorporating Single-Use Technologies
To define the necessary capacity of the facility, the primary question is how many batches per product per year are needed? However, this number has not always been defined when the facility design st…
Article
Optimizing Resin Performance with Disposable Chromatography Solutions
Where we have seen significant advances in chromatography is with innovative new Protein A-derived media that are delivering improved capacity and stability, helping to increase production efficiency,…
Article
Relationship Building at Top of Mind for Clients
As results from BioPlan Associates’ 11th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production (1) show, however, it’s no longer enough for CMOs to lay claim to technolog…
Article
2014 Manufacturing Trends and Outlook
More than half of all respondents said their companies increased biomanufacturing capacity in 2013. Less than 3% reported a drop in production. Only 8.1% said their companies decreased spending for bi…