Search results for " capacity"
Article
Modern Manufacturing Key to More Effective Vaccines
He said these developments will “transform the biopharmaceutical industry” by boosting local production and supply of high-quality vaccines in developing countries, while also expanding capacity for r…
Article
Taking Prepacked Columns to Manufacturing Scale
Prepacked chromatography columns in biomanufacturing can save time, but also present concerns related to delivery lead times, capacity, and operational cost.
Learn more here about ways to address…
Article
Reliability Rooms and the Move to Proactive Supply Chain Management
In some cases, their internal performance is monitored in terms of capacity utilization, schedule attainment, raw material and work-in-progress levels, as well as audit status.
These data provi…
Article
ADC Development Robust Despite Lackluster Performance
Multiple molecules of this polymer-payload construction (Dolaflexin) can then be attached to the chosen mAb, which results in an ADC with a significantly increased payload capacity, according to the c…
Poster
A Next Generation Protein A Chromatography Resin for Improved Productivity and Bioburden Control
The binding capacity has been increased more than 40% compared to its predecessor MabSelect SuRe LX enabling increased mass throughput and productivity.
Read more here
Poster
Fast Trak Services: a collaborative project to accelerate downstream biosimilar process development
To improve the availability, price and access of medicines, many countries are implementing strategies to establish their own production capacity.
To support this development, mAbxience, a Sp…
Article
Fusion Proteins Pose Manufacturability Challenges
The unique structures of fusion proteins lead to expression, heterogeneity, and stability issues.
By Cynthia A. Challener
Fusion proteins are engineered proteins that contain domains from di…
Poster
Evaluation of Protein A resin lifetime during extensive use (overloading) in continuous chromatography mode
In recent years, continuous chromatography has emerged as an alternative to batch operations to improve productivity or increase resin capacity utilization of chromatography purification processes. …
Article
Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
They are able to flow at fast rates, albeit with low binding capacity.
Taken together, upstream and downstream process innovations can be packaged into an automated, continuous, small-footprint an…
Article
Single-use Bioreactors Have Reached the Big Time
The decision to use disposable bioreactors is now driven by commercial rather than technological considerations.
By Cynthia A. Challener
Single-use bioreactors available from various vendors…