Search results for " resins" in Articles / App Notes
Article
Accelerated flavivirus vaccine production with modern tools and solutions
For downstream processing, modern chromatography resins offer high selectivity and excellent pressure-flow properties for high productivity inmanufacturing-scale purifications. This white paper includ…
Article
Evaluating E&L Studies for Single-Use Systems
Extractables studies on the chromatographic resins were already available from the vendors so all resins involved in the purification process were disconnected and excluded from the extraction study, …
Article
High-Throughput Process Development Handbook
Time-to-clinic and time-to-market are two key factors for successful biopharmaceutical development. Efficient development of the manufacturing process is a crucial component of the overall project…
Article
Technology solutions simplifying chromatography unit operations
Chromatography operations typically involve steps such as resin slurry preparation, column packing, cleaning, unpacking, and resin storage. While each of the aforementioned steps can potentially be …
Article
Downstream Processing Continues to Worry CMOs
A majority of CMOs are considering:
• Use of high capacity resins
• In-line buffer dilution systems
• Single-use disposable tangential flow filtration (TFF) membranes
• Single use-prep…
Article
ReadyToProcess™ Prepacked Columns
ReadyToProcess columns are high-performance bioprocessing columns prepacked with a range of bioprocess resin and are supplied ready for use. As a supplier of both the chromatography resin and the pr…
Article
A Platform Approach for the Identity Testing of Multi-Component Cell-Culture Media
A similar approach was proposed for chromatography resins in another, separate study, but employed different methods (22). As mentioned previously, compendial microbiological tests were not included i…
Article
Selecting the Right Viral Clearance Technology
“These disposable membranes remove the need for evaluation of sanitization steps and the need to evaluate aged resins. In addition, the risk of a potential viral contaminant being carried over from ru…
Article
Securing the Single-Use Supply Chain
Dual sourcing is one of many possible solutions to securing the supply chain.
Single-use systems (SUS) have become established in biopharmaceutical drug development. As confidence in the technol…
Article
Challenges of Protein Aggregation During Purification
Careful selection of downstream processing conditions is a must.
Sep 1, 2014
By: Cynthia Challener, PhD
BioPharm International
Volume 27, Issue 9, pp. 32-35
Removal of protein a…