Search results for " resins"
Article
Developing a HIC polishing step for removal of mAb aggregates
This article describes the development of a flow-through (FT) polishing step using hydrophobic interaction chromatography (HIC) to remove mAb aggregates.
It includes:
- The use of HTPD plate…
Article
How to Use Multiwell Plates With Manual Operation
High-throughput tools like PreDictor™ plates prefilled with chromatography resins make it possible to explore a large characterized space for optimizing process conditions. They save time and require …
Webcast
Optimizing a HIC step with HTPD
This webinar discusses a step-by-step workflow for optimizing a hydrophobic interaction chromatography (HIC) step.
Article
Webinar: Optimizing a HIC step with HTPD
Webinar date: Wed, Mar 8, 2023 11:00 AM EST (5:00 PM CET)
This webinar discusses a step-by-step workflow for optimizing a hydrophobic interaction chromatography (HIC) step.
Thi…
Article
Choose your Optimal Wavelength for Chromatography
ÄKTA™ chromatography systems and resins offer a wide range of solutions for isolating and purifying target molecules from research, through process development and manufacturing. With a variety…
Article
Download your Mechanistic Modeling eBook
What is mechanistic modeling in chromatography?
Mechanistic models use computer simulations to decrease the number of experiments needed during process development. The simulatio…
Article
Optimization of a HIC step for recombinant protein purification
Follow this step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).
…
Article
Capture of Bispecific Antibodies and Removal of Product-Related Impurities
The biotherapeutics pipeline is becoming increasingly diverse as antibody variants such as bispecifics, conjugates, and fragments move through preclinical stages to commercial manufacturin…
Article
New hydrophobic interaction chromatography (HIC) handbook
The role of this technique in protein purification in the lab and at bioprocess scale, the principle of the technique, and the equipment and resins needed are described in this detailed handbook.
…
Article
Chromatography innovations for the diverse antibody pipeline
In this video Josefin Bolik, global product manager — antibody capture at Cytiva, presents how to select resins for your antibody variant purification project.
WATCH THE VIDEO >>