Search results for " cell" in Articles / App Notes
Article
Faster Flavivirus Vaccine Production
The approach helps determine which components in the media will have the most beneficial effect on cell growth. Surface Plasmon Resonance (SPR) analysis during process development provides data about …
Article
Scale-Up Model of a mAb Process from Microbioreactor to XDR-1000
All investigated bioreactor systems displayed similar trends over time and acceptable variability between cultures for viable cell density and viability profile, product titer, lactate, and product qu…
Article
Webinar On Demand: Expanding SPR Uses in Antibody Effector Function Determination
CQAs typically include data on how the candidate interacts with target proteins, as well as process-related CQAs such as protein size, homogeneity, presence of host cell proteins (HCP) etc.
In th…
Article
Case Study: Process for Production of Oncolytic Adenovirus
The case study describes a process from upstream cell culture to downstream purification, using scalable modern tools and technologies.
Read the case study on "Process for Production of Oncolytic…
Article
Biomanufacturing: The Cost of Unskilled Workers
Advances in cell and gene therapies are predicted to disrupt the biomanufacturing industry, requiring new techniques and technologies to be established. The need for process development expertise incr…
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Modeling the Degradation of mAb Therapeutics
They result in instabilities that can occur at various stages of product development, including upstream processing (during protein expression in cell culture), downstream processing (purification), p…
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Cytiva Opens Biotechnology Manufacturing Center in UK
…ins an open laboratory aimed at providing SBC tenants with affordable access to advanced protein and cell analysis technologies.
Article
Using Multiple Techniques in Biosimilar Analysis
(Figures courtesy of the author)
Experiments were also conducted on a Bruker Tensor 37 FTIR instrument with a photovoltaic MCT detector, using an AquaSpec cell; structural fitting was done via …
Article
Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
Additionally, substantial improvements to exoglycosidase manufacturing process and quality are enabling these enzymes to play important roles in other clinically important areas, such as cellular or p…
Article
Developing an Efficient Adenovirus Downstream Purification Process
This application note describes the development of downstream chromatography steps for purification of adenovirus from HEK293 cell culture harvest.
To read the application note click her…