Search results for " cell"
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Biopharma Outsourcing Activities Update
This increased outsourcing is also the case for areas such as cell line development and downstream process development.
Moreover, expectations surrounding future levels of outsourcing activity rema…
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Q&A with Industry Leaders: Rita Peters
One example is Cytiva’s acquisition of the HyClone line cell culture media, sera, and process liquids; Dharmacon RNAi gene modulation, products; and Sera-Mag magnetic beads. With the changes in compan…
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EMA Collaborates with HTA Assessment Networks
Belgium, a cell-therapy specialist, has achieved reimbursement deals for the product in only three European countries--Belgium, Netherlands, and Spain, all of which it has facilities in.
“Gaining r…
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Determining Criticality, Part Two: DoE and Data-Driven Criticality
For example, to perform a multivariate study on a fermentation unit operation, additional processing through cell lysis and purification unit operations is needed so that CQAs may be sampled and teste…
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Predicting Progress in Protein Aggregation
There are ongoing studies aimed at developing sophisticated cell-based assays for the evaluation of the immune response to protein aggregates, but despite some preliminary links between in vitro data …
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Best Practices in Adopting Single-Use Systems
Key considerations for implementing single-use components or platforms when moving from research to process development.
The adoption of single-use systems in biopharmaceutical production or…
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ReadyToProcess WAVE 25 Bioreactor System
The system is based on a well-known rocking technology that provides mixing and aeration to the culture, which is maintained in an inflated, disposable Cellbag bioreactor cultivation chamber.
With…
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Trends in Downstream Bioprocessing
It involves the removal of insoluble cell debris and particulates; product isolation through extraction, adsorption, ultrafiltration, or precipitation; product purification through affinity chromatogr…
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Essentials in Establishing and Using Design Space
Knowledge of product or process acceptance criterion is crucial in design space.
Design space is generally considered to be the areas where the product or process parameters can be run safe…
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Report from the Eighth International Plasma Product Biotechnology Meeting Melia Salinas, Lanzarote, Spain
One hypothesis discussed by Alan was that IVIg may interact with activating FcRs on dendritic cells in the initiation of its effects.
Jan Over from Sanquin gave an insightful presentation on…