Search results for " cell"
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Advances in Sterilization Technologies for Overcoming Viral-Vector Manufacturing Challenges
Sterility must be assured for all biologic drug products. Terminal sterilization achieved via treatment with heat, radiation, or certain chemicals (vaporous hydrogen peroxide, vaporous peracet…
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Unraveling the secrets of poloxamer 188 - A webinar mystery
When an inexplicable drop in cell culture performance is linked to a batch of media, researchers race to find the culprit.
In this on demand recording we will unravel the mystery as we …
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Right the First Time: Bioreactor Scale and Design Translation
Cell culture processes need to operate in a design space where the oxygen supply and carbon dioxide removal can match cellular metabolism. In addition, prohibitive high shear stress and high gas flow …
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A Look into Biologic Scale-Up Strategies
To maximize cell-culture output, strategy is required that takes into consideration factors such as cell culture media, environmental monitoring, and process controls. Yet, despite decades of process …
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Better bioprocess scaleup with Bioreactor Scaler Pro
Are you still using the manual input, trial-and-error method when scaling your cell culture process, spending long hours in the lab analyzing uncertain data?
With Bioreactor Scaler Pr…
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On-demand webinar: Balancing innovation, speed, and robustness to improve efficiency in upstream process development
Watch it now, on demand! We'll cover strategies like cell line development, media development, and raw material characterization to help you make your process more efficient.
Sign up and view th…
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What is process development?
For example, a suspension cell culture is easier to scale up compared to adherent cells. And ultracentrifugation to separate empty from full capsids of adeno-associated virus (AAV) does not scale well…
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Working With Advanced Therapeutics: You Bring the Idea, We Bring the Map
Plasmids. mRNA. Oligos. Cell and gene therapies. Antibody variants. Vaccines. We all know these advanced therapies hold huge potential. But developing them isn’t straightforward, and fai…
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Accelerating VLP purification process development
Indeed, a method for the large-scale production of VLPs is production in suspension cell culture, and extracting the VLPs from the cell culture supernatant is a time and labor-intensive process.
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Regulatory Requirements for Safe and Efficient Biologic Drug Development
Another thing to look at is from the cell and gene therapy area. FDA has issued a lot of guidance earlier in 2020 that’s affected the cell and gene manufacturing area, since we have a huge amount of r…