Search results for " control" in Articles / App Notes
Article
Report from the Eighth International Plasma Product Biotechnology Meeting Melia Salinas, Lanzarote, Spain
Key considerations such as LEAN, multipurpose and flexibility was designed and built in to the facility from start, ensuring high capacity, microbial control and tracing of all filled vials. During th…
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A Look Ahead at BioPharma Manufacturing and Regulation
FDA is currently pursuing additional pathways to ease postapproval changes for well-understood and controlled processes under a robust quality system.
Continuous manufacturing, althoug…
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Analytical Considerations for Successful Upstream Process Development with Spivey and Lane
… data is in a pilot-plant environment, it has to find its way onto a historian or some other process control and monitoring system within the commercial or development laboratories where they're coll…
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Implementing Inline Conditioning to Advance Process Intensification
Looking into the future, are there some aspects of the IC technology you want to investigate further, or intend to implement next?
We validated and used in GMP batches IC technology by flow cont…
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Cell-free Expression Systems Pose Cell Culture Alternative
The professors collectively believe that cell-free protein expression offers increased control and flexibility compared to traditional cell-based bioprocessing. DeLisa also emphasizes that “cell-free …
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Updating Viral Clearance for New Biologic Modalities
This is accomplished by controlling liquid flow during a VRF step based upon the pressure differential across the VRF filter itself, says Berrie. So far, he adds, this approach has improved overall pr…
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Technology Innovations Improve Process Chromatography Performance
… of single-use technologies, better characterization of raw materials, and the use of more precisely controlled bioreactors, improvements in downstream processing have not kept pace, says Nandu Deork…
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Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Raw material quality control (QC) testing can also be reduced or eliminated by implementing single-use technologies, saving time from reduced process steps as well as labor costs.
The increa…
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Biomanufacturing: Demand for Continuous Bioprocessing Increasing
- Improved quality: Biological molecules are expressed continuously, and compared to batch culture, continuous culture tends to be more controllable, less intense and stressful, including less shear a…
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Cell-Culture Advances Test Bioreactor Performance Models
Some of the challenges with perfusion processes include sensor instability and fouling over the course of the culture, which impacts the ability to effectively monitor and control these processes, acc…