Search results for "single-use" in Articles / App Notes
Article
Process Chromatography: Continuous Optimization
Single-use chromatography is another challenging area. “To date it has been difficult to provide cost-effective devices that can also be scaled up,” notes Bulpin.
Purification processes for mAbs h…
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Hybrid Bioprocessing: A Q&A with Andrew Sinclair
In my view, it's where within the manufacturing process, there are a combination of single-use (SU) materials and re-usable materials in contact with the process and associated fluids. This often refe…
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Accelerated flavivirus vaccine production with modern tools and solutions
Single-use production bioreactors and chromatography purification columnsmitigate cross-contamination risk and support increased operator safety, while reducing time to market by eliminating costly an…
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Efficient concentration of a low-titer bovine IgG with high recovery in low volume
The use of ReadyCircuit™ single-use assemblies allowed for aseptic connectivity of the filtration device. Filtration was performed using ReadyToProcess™ hollow fiber filter cartridges. The described …
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Biopharma in 2016: Higher Quality Drugs, Less Expensive Manufacturing
This includes single-use technology, which has been shown to reduce capital and operating costs by 40%-50%,1 and modular and flexible manufacturing systems, which are seen by many as a way for biophar…
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Validation of the production of influenza virus in ReadyToProcess WAVE™ 25 bioreactor system
This application note describes the validation of the single-use ReadyToProcess WAVE 25 rocking bioreactor system in production of influenza virus from Vero cells in microcarrier-based cultures. A 2…
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Perfusion in the 21st Century
Perfusion processes are also seen as better suited to meet the needs of flexible, often single-use, multiproduct manufacturing facilities. Such manufacturing sites generally have smaller reactors and …
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Managing Biomanufacturing Capacity Expectations
BioPlan found that the development of more efficient single-use products, better downstream purification technologies, the introduction of continuous downstream operations, and increased modularizatio…
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Aseptic Processing: Keeping it Safe
Single-use containers for aseptic processing—such as filters, tubing, connectors, and bags to hold bulk products—are already relatively common in aseptic filling, and can also help keep contamination …
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Risk Assessment and Mitigation in Biopharmaceutical Manufacturing
BioPharm: Does the use of single-use systems (SUS) and/or equipment present any specific challenges or considerations when performing a risk assessment?
AstraZeneca: The use of SUS removes some of…